Openly accessible

Effects of beacon administration on energy expenditure and substrate utilisation in Psammomys obesus (Israeli sand rats)

Walder, Ken, McMillan, Janine, Lee, Scott, Civitarese, Anthony, Zimmet, Paul and Collier, Gregory 2001, Effects of beacon administration on energy expenditure and substrate utilisation in Psammomys obesus (Israeli sand rats), International journal of obesity, vol. 25, no. 9, pp. 1281-1285.

Attached Files
Name Description MIMEType Size Downloads
walder-effectsof-2001.pdf Published version application/pdf 403.57KB 1

Title Effects of beacon administration on energy expenditure and substrate utilisation in Psammomys obesus (Israeli sand rats)
Formatted title Effects of beacon administration on energy expenditure and substrate utilisation in Psammomys obesus (Israeli sand rats)
Author(s) Walder, Ken
McMillan, Janine
Lee, Scott
Civitarese, Anthony
Zimmet, Paul
Collier, Gregory
Journal name International journal of obesity
Volume number 25
Issue number 9
Start page 1281
End page 1285
Publisher Newman Pub. Ltd.
Place of publication London, England
Publication date 2001-09
ISSN 0307-0565
1476-5497
Keyword(s) beacon
Psammomys obesus
calorimetry
physical activity
energy expenditure
adipose tissue
Summary Objective: To investigate whether beacon administration affects substrate utilisation, physical activity levels or energy expenditure in Psammomys obesus. Design: Pairs of age- and sex-matched Psammomys obesus were randomly assigned to either beacon-treated (15 µg/day for 7 days (i.c.v.)) or control (i.c.v. saline) groups. Measurements: Indirect calorimetry on day 0 and day 7 to measure oxygen consumption and carbon dioxide production, which were used to calculate fat oxidation, carbohydrate oxidation and total energy expenditure. Physical activity in the calorimeter was measured using an infrared beam system. Food intake and body weight were measured daily. Results: The administration of beacon significantly increased body weight compared to saline-treated control animals. This body weight gain was primarily due to increased body fat content. Average daily food intake tended to be higher in beacon-treated Psammomys obesus, but no effect of beacon administration on substrate oxidation, activity or energy expenditure was detected. Conclusion: The effects of beacon on body weight are due to increased food intake, with no detectable effect on nutrient partitioning, physical activity or energy expenditure.
Language eng
Field of Research 111716 Preventive Medicine
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2001, Nature Publishing Group
Persistent URL http://hdl.handle.net/10536/DRO/DU:30001172

Document type: Journal Article
Collections: School of Health Sciences
Open Access Collection
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.

Versions
Version Filter Type
Citation counts: Scopus Citation Count Cited 11 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 447 Abstract Views, 1 File Downloads  -  Detailed Statistics
Created: Mon, 07 Jul 2008, 07:32:35 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.