Fuzzy logic provides a mathematical formalism for a unified treatment of vagueness and imprecision that are ever present in decision support and expert systems in many areas. The choice of aggregation operators is crucial to the behavior of the system that is intended to mimic human decision making. This paper discusses how aggregation operators can be selected and adjusted to fit empirical data—a series of test cases. Both parametric and nonparametric regression are considered and compared. A practical application of the proposed methods to electronic implementation of clinical guidelines is presented
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