Strategies and methods for the attachment of amino acids and peptides to chiral [n]polynorbornane templates

Pfeffer, Frederick and Russell, Richard. A. 2003, Strategies and methods for the attachment of amino acids and peptides to chiral [n]polynorbornane templates, Organic and biomolecular chemistry, vol. 1, pp. 1845-1851.

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Title Strategies and methods for the attachment of amino acids and peptides to chiral [n]polynorbornane templates
Author(s) Pfeffer, Frederick
Russell, Richard. A.
Journal name Organic and biomolecular chemistry
Volume number 1
Start page 1845
End page 1851
Publisher Royal Society of Chemistry
Place of publication Cambridge, England
Publication date 2003
ISSN 1477-0520
1477-0539
Summary A versatile synthesis of amino acid and peptide functionalised [n]polynorbornane scaffolds is described. The frameworks are constructed using the stereoselective and regioselective cycloaddition of suitably functionalised chiral cyclobutene epoxides with similar norbornenes. The strategies employed allow a range of topologies to be accessed and a number of regioselectively addressable linkage points to be accommodated.
Notes First published as an Advance Article on the web 25th April 2003
Language eng
Field of Research 030503 Organic Chemical Synthesis
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©Royal Society of Chemistry, 2003
Persistent URL http://hdl.handle.net/10536/DRO/DU:30002198

Document type: Journal Article
Collection: School of Biological and Chemical Sciences
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