Near normalisation of lumbar spine bone density in young women with osteopenia recovered from adolescent onset anorexia nervosa: a longitudinal study

Bass, Shona, Saxon, Leanne, Corral, Anne-Marie, Rodda, Christine P., Strauss, Boyd J. G., Reidpath, Daniel and Clarke, Caroline 2005, Near normalisation of lumbar spine bone density in young women with osteopenia recovered from adolescent onset anorexia nervosa: a longitudinal study, Journal of pediatric endocrinology and metabolism, vol. 18, no. 9, pp. 897-907.

Attached Files
Name Description MIMEType Size Downloads

Title Near normalisation of lumbar spine bone density in young women with osteopenia recovered from adolescent onset anorexia nervosa: a longitudinal study
Author(s) Bass, Shona
Saxon, Leanne
Corral, Anne-Marie
Rodda, Christine P.
Strauss, Boyd J. G.
Reidpath, Daniel
Clarke, Caroline
Journal name Journal of pediatric endocrinology and metabolism
Volume number 18
Issue number 9
Start page 897
End page 907
Publisher Freund Publishing House Ltd.
Place of publication Tel Aviv, Israel
Publication date 2005
ISSN 0334-018X
Keyword(s) bone density
bone size
growth and development
nutrition
anorexia nervosa
Summary To investigate the effect of the progression of adolescent onset anorexia nervosa (AN) on bone parameters we followed two cohorts (Disease cohort and recovered cohort) of adolescents for a total of 5.2 years. In the 'Disease' cohort (n = 18), lumbar spine bone density (BMD) was reduced by 0.6 SD after 0.8 years of disease and was reduced a further 1.0 SD after a total 2.5 years of disease (p < 0.001). At the third lumbar vertebra there was bone loss (-3.7%, p < 0.05) resulting in reduced volumetric BMD (-5.1%, p < 0.08). In the 'recovered' cohort, lumbar spine BMD was reduced by 1.9 SD after 1.7 years of disease, and increased by 1.5 SD after 2.7 years of recovery (p < 0.001). At the third lumbar vertebra there was an increase in bone mass (20.5%, p < 0.001) and bone volume (14.1%, p < 0.001), resulting in increased volumetric BMD (6.3%, p < 0.08). Normalisation of lumbar spine BMD may be achieved in patients with adolescent onset AN when the successful recovery of body weight is combined with the return of regular menses.
Language eng
Field of Research 110602 Exercise Physiology
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2005, Freund Publishing House Ltd.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30003107

Document type: Journal Article
Collection: School of Exercise and Nutrition Sciences
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: Scopus Citation Count Cited 24 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 551 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Mon, 07 Jul 2008, 08:43:34 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.