Chemiluminescence methods for the determination of ofloxacin

Francis, Paul and Adcock, Jacqui L. 2005, Chemiluminescence methods for the determination of ofloxacin, Analytica chimica acta, vol. 541, no. 1-2, pp. 3-12.

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Title Chemiluminescence methods for the determination of ofloxacin
Author(s) Francis, Paul
Adcock, Jacqui L.
Journal name Analytica chimica acta
Volume number 541
Issue number 1-2
Start page 3
End page 12
Publisher Elsevier BV
Place of publication Amsterdam, The Netherlands
Publication date 2005-06-13
ISSN 0003-2670
1873-4324
Keyword(s) ofloxacin
fluoroquinolones
flow-injection analysis
chemiluminescence spectra
Summary Ofloxacin is a synthetic fluoroquinolone antibiotic that has been used in the treatment of respiratory tract, urinary tract and tissue-based infections. Methodology for the determination of ofloxacin based on chemiluminescence detection can be divided into: direct oxidation with tris(2,2′-bipyridyl)ruthenium(III) or permanganate; and enhancement of the emission from either the oxidation of sulfite or the reaction between sodium nitrite and hydrogen peroxide. In this paper, we compare the analytical methodology and evaluate the light-producing pathways that have been proposed for these reactions.
Language eng
Field of Research 030103 Flow Analysis
Socio Economic Objective 970103 Expanding Knowledge in the Chemical Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2005, Elsevier BV
Persistent URL http://hdl.handle.net/10536/DRO/DU:30003176

Document type: Journal Article
Collection: School of Biological and Chemical Sciences
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