Deakin home > Deakin University Library > Deakin Research Online > Long-term effects of calcium-vitamin-D3-fortified milk on bone geometry and strength in older men

Long-term effects of calcium-vitamin-D3-fortified milk on bone geometry and strength in older men

Daly, Robin, Bass, Shona and Nowson, Caryl 2006, Long-term effects of calcium-vitamin-D3-fortified milk on bone geometry and strength in older men, Bone, vol. 39, no. 4, pp. 946-953.

Attached Files (Some files may be inaccessible until you login with your Deakin Research Online credentials)
Name Description MIMEType Size Downloads

Title Long-term effects of calcium-vitamin-D3-fortified milk on bone geometry and strength in older men
Author(s) Daly, Robin
Bass, Shona
Nowson, Caryl
Journal name Bone
Volume number 39
Issue number 4
Start page 946
End page 953
Publisher Elsvier Inc.
Place of publication New York, NY.
Publication date 2006-10
ISSN 8756-3282
Keyword(s) milk supplementation
calcium
vitamin D
men
bone geometry
QCT
Summary The long-term effects of calcium and vitamin D supplementation on bone material and structural properties in older men are not known. The aim of this study was to examine the effects of high calcium (1000 mg/day)- and vitamin-D3 (800 IU/day)-fortified milk on cortical and trabecular volumetric BMD (vBMD) and bone geometry at the axial and appendicular skeleton in men aged over 50 years. One hundred and eleven men who were part of a larger 2-year randomized controlled trial had QCT scans of the mid-femur and lumbar spine (L1–L3) to assess vBMD, bone geometry and indices of bone strength [polar moment of inertia (Ipolar)]. After 2 years, there were no significant differences between the milk supplementation and control group for the change in any mid-femur or L1–L3 bone parameters for all men aged over 50 years. However, the mid-femur skeletal responses to the fortified milk varied according to age, with a split of ≤62 versus >62 years being the most significant for discriminating the changes between the two groups. Subsequent analysis revealed that, in the older men (>62 years), the expansion in mid-femur medullary area was 2.8% (P < 0.01) less in the milk supplementation compared to control group, which helped to preserve cortical area in the milk supplementation group (between group difference 1.1%, P < 0.01). Similarly, for mid-femur cortical vBMD and Ipolar, the net loss was 2.3 and 2.8% less in the milk supplementation compared to control group (P < 0.01 and <0.001, respectively). In conclusion, calcium–vitamin-D3-fortified milk may represent an effective strategy to maintain bone strength by preventing endocortical bone loss and slowing the loss in cortical vBMD in elderly men.
Notes Available online 24 May 2006.
Language eng
Field of Research 111716 Preventive Medicine
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2006, Elsevier Inc.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30003600

Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in Deakin Research Online is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 18 times in TR Web of Science
Scopus Citation Count Cited 15 times in Scopus
Access Statistics: 393 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Mon, 07 Jul 2008, 08:57:47 EST