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Development and application of model of resource utilization, costs, and outcomes for stroke (MORUCOS): an Australian economic model for stroke.

Mihalopoulos, Catherine, Cadilhac, Dominique, Moodie, Marjory, Dewey, Helen, Thrift, Amanda, Donnan, Geoffrey and Carter, Robert 2005, Development and application of model of resource utilization, costs, and outcomes for stroke (MORUCOS): an Australian economic model for stroke., International journal of technology assessment in health care, vol. 21, no. 4, pp. 499-505.

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Title Development and application of model of resource utilization, costs, and outcomes for stroke (MORUCOS): an Australian economic model for stroke.
Author(s) Mihalopoulos, Catherine
Cadilhac, Dominique
Moodie, Marjory
Dewey, Helen
Thrift, Amanda
Donnan, Geoffrey
Carter, Robert
Journal name International journal of technology assessment in health care
Volume number 21
Issue number 4
Start page 499
End page 505
Publisher Cambridge University Press
Place of publication Cambridge, England
Publication date 2005-10
ISSN 0266-4623
1471-6348
Keyword(s) cerebrovascular disorders
economic model
cost benefit analysis
Summary Objectives: To outline the development, structure, data assumptions, and application of an Australian economic model for stroke (Model of Resource Utilization, Costs, and Outcomes for Stroke [MORUCOS]). Methods: The model has a linked spreadsheet format with four modules to describe the disease burden and treatment pathways, estimate prevalence-based and incidence-based costs, and derive life expectancy and quality of life consequences. The model uses patient-level, community-based, stroke cohort data and macro-level simulations. An interventions module allows options for change to be consistently evaluated by modifying aspects of the other modules. To date, model validation has included sensitivity testing, face validity, and peer review. Further validation of technical and predictive accuracy is needed. The generic pathway model was assessed by comparison with a stroke subtypes (ischemic, hemorrhagic, or undetermined) approach and used to determine the relative cost-effectiveness of four interventions. Results: The generic pathway model produced lower costs compared with a subtypes version (total average first-year costs/case AUD$15,117 versus AUD$17,786, respectively). Optimal evidence-based uptake of anticoagulation therapy for primary and secondary stroke prevention and intravenous thrombolytic therapy within 3 hours of stroke were more cost-effective than current practice (base year, 1997). Conclusions: MORUCOS is transparent and flexible in describing Australian stroke care and can effectively be used to systematically evaluate a range of different interventions. Adjusting results to account for stroke subtypes, as they influence cost estimates, could enhance the generic model.
Notes Reproduced with the specific permission of the copyright owner
Language eng
Field of Research 110904 Neurology and Neuromuscular Diseases
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2005, Cambridge University Press
Persistent URL http://hdl.handle.net/10536/DRO/DU:30004086

Document type: Journal Article
Collections: School of Health and Social Development
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