Fruit and vegetable consumption and stroke : meta-analysis of cohort studies

He, Feng J., Nowson, Caryl A. and MacGregor, Graham A. 2006, Fruit and vegetable consumption and stroke : meta-analysis of cohort studies, Lancet, vol. 367, no. 9507, pp. 320-326.

Attached Files
Name Description MIMEType Size Downloads

Title Fruit and vegetable consumption and stroke : meta-analysis of cohort studies
Author(s) He, Feng J.
Nowson, Caryl A.
MacGregor, Graham A.
Journal name Lancet
Volume number 367
Issue number 9507
Start page 320
End page 326
Publisher Elsevier
Place of publication New York, NY.
Publication date 2006-01-28
ISSN 0140-6736
1474-547X
Summary Background
Increased consumption of fruit and vegetables has been shown to be associated with a reduced risk of stroke in most epidemiological studies, although the extent of the association is uncertain. We quantitatively assessed the relation between fruit and vegetable intake and incidence of stroke in a meta-analysis of cohort studies.

Methods

We searched MEDLINE, EMBASE, the Cochrane Library, and bibliographies of retrieved articles. Studies were included if they reported relative risks and corresponding 95% CIs of stroke with respect to frequency of fruit and vegetable intake.

Findings
Eight studies, consisting of nine independent cohorts, met the inclusion criteria. These groups included 257 551 individuals (4917 stroke events) with an average follow-up of 13 years. Compared with individuals who had less than three servings of fruit and vegetables per day, the pooled relative risk of stroke was 0·89 (95% CI 0·83–0·97) for those with three to five servings per day, and 0·74 (0·69–0·79) for those with more than five servings per day. Subgroup analyses showed that fruit and vegetables had a significant protective effect on both ischaemic and haemorrhagic stroke.

Interpretation
Increased fruit and vegetable intake in the range commonly consumed is associated with a reduced risk of stroke. Our results provide strong support for the recommendations to consume more than five servings of fruit and vegetables per day, which is likely to cause a major reduction in strokes.


Language eng
Field of Research 111199 Nutrition and Dietetics not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2006, Elsevier
Persistent URL http://hdl.handle.net/10536/DRO/DU:30006534

Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 335 times in TR Web of Science
Scopus Citation Count Cited 369 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 459 Abstract Views, 2 File Downloads  -  Detailed Statistics
Created: Thu, 31 Jul 2008, 10:41:10 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.