Prevention of type 2 diabetes in a primary health care setting interim results from the Greater Green Triangle (GGT) Diabetes Prevention Project

Kilkkinen, Annamari, Heistaro, Sami, Laatikainen, Tiina, Janus, Edward, Chapman, Anna, Absetz, Pilvikki and Dunbar, James 2007, Prevention of type 2 diabetes in a primary health care setting interim results from the Greater Green Triangle (GGT) Diabetes Prevention Project, Diabetes research and clinical practice, vol. 76, no. 3, pp. 460-462.

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Title Prevention of type 2 diabetes in a primary health care setting interim results from the Greater Green Triangle (GGT) Diabetes Prevention Project
Author(s) Kilkkinen, Annamari
Heistaro, Sami
Laatikainen, Tiina
Janus, Edward
Chapman, Anna
Absetz, Pilvikki
Dunbar, James
Journal name Diabetes research and clinical practice
Volume number 76
Issue number 3
Start page 460
End page 462
Publisher Elsevier Ireland Ltd
Place of publication Limerick, Ireland
Publication date 2007-06
ISSN 0168-8227
1872-8227
Keyword(s) type 2 diabetes mellitus
life style
intervention studies
primary prevention
primary health care
Summary Although clinical trials have shown that lifestyle modifications reduce the risk of type 2 diabetes, translating lessons from trials to primary care remains a challenge. The aim of the study was to evaluate efficacy and feasibility of primary care-based diabetes prevention model with modest resource requirements in rural Australia. Three hundred and eleven subjects with at least a moderate risk of type 2 diabetes participated in a combined dietary and physical activity intervention. Clinical measurements and fasting blood samples were taken at the baseline and after intervention. After 3 months intervention, total (change −3.5%, p < 0.001) and LDL cholesterol (−4.8%, p < 0.001) plasma levels as well as body mass index (−2.5%, p < 0.001), weight (−2.5%, p < 0.001), and waist (−1.6%, p < 0.001) and hip (−2.7%, p < 0.001) circumferences reduced significantly. A borderline reduction was found in triglyceride levels (−4.8%, p = 0.058) while no changes were observed in HDL cholesterol (+0.6%, p = 0.525), glucose (+0.06%, p = 0.386), or systolic (−0.98%, p = 0.095) or diastolic (−1.06%, p = 0.134) blood pressure levels. In conclusion, a lifestyle intervention improved health outcomes – especially obesity and blood lipids – in a population at high risk of developing type 2 diabetes. Our results suggest that the present model is effective and feasible to carry out in primary care settings.
Language eng
Field of Research 111717 Primary Health Care
Socio Economic Objective 920299 Health and Support Services not elsewhere classified
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2006, Elsevier Ireland Ltd
Persistent URL http://hdl.handle.net/10536/DRO/DU:30007117

Document type: Journal Article
Collection: School of Health and Social Development
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