An evaluation of contemporary hidden Markov model genefinders with a predicted exon taxonomy

Knapp, Keith and Chen, Yi-Ping Phoebe 2007, An evaluation of contemporary hidden Markov model genefinders with a predicted exon taxonomy, Nucleic acids research, vol. 35, no. 1, pp. 317-324.

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Title An evaluation of contemporary hidden Markov model genefinders with a predicted exon taxonomy
Author(s) Knapp, Keith
Chen, Yi-Ping Phoebe
Journal name Nucleic acids research
Volume number 35
Issue number 1
Start page 317
End page 324
Publisher Oxford University Press
Place of publication Oxford, England
Publication date 2007
ISSN 0305-1048
1362-4962
Summary We present an independent evaluation of six recent hidden Markov model (HMM) genefinders. Each was tested on the new dataset (FSH298), the results of which showed no dramatic improvement over the genefinders tested five years ago. In addition, we introduce a comprehensive taxonomy of predicted exons and classify each resulting exon accordingly. These results are useful in measuring (with finer granularity) the effects of changes in a genefinder. We present an analysis of these results and identify four patterns of inaccuracy common in all HMM-based results.
Notes Published online Dec.14 2006
Language eng
Field of Research 080199 Artificial Intelligence and Image Processing not elsewhere classified
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2006, The Authors
Persistent URL http://hdl.handle.net/10536/DRO/DU:30007571

Document type: Journal Article
Collection: School of Engineering and Information Technology
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