Localization and expression of selenoprotein S in the testis of Psammomys obesus

Windmill, Kelly F., Tenne-Brown, Janette, Bayles, Richard, Trevaskis, James, Gao, Yuan and Walder, Ken 2007, Localization and expression of selenoprotein S in the testis of Psammomys obesus, Journal of molecular histology, vol. 38, no. 1, pp. 97-101.


Title Localization and expression of selenoprotein S in the testis of Psammomys obesus
Author(s) Windmill, Kelly F.
Tenne-Brown, Janette
Bayles, Richard
Trevaskis, James
Gao, Yuan
Walder, Ken
Journal name Journal of molecular histology
Volume number 38
Issue number 1
Start page 97
End page 101
Publisher Springer Netherlands
Place of publication Amsterdam, The Netherlands
Publication date 2007-03
ISSN 1567-2379
1567-2387
Keyword(s) Selenoprotein
SEPS1
testis
spermatogenesis
Summary Selenium is an essential trace element and selenoprotein S is a member of the selenoprotein family that has the non-standard amino acid selenocysteine incorporated into the polypeptide. Dietary selenium has been shown to play an important protective role in a number of diseases including cancer, immune function and the male reproductive system. In this study, we have observed high levels of selenoprotein S gene expression in the testis from Psammomys obesus. Real-time PCR and immunofluorescence demonstrate that selenoprotein S expression is low in testes from 4-week-old animals but increases significantly by 8 weeks of age and remains high until 17 weeks of age. Selenoprotein S protein is detected in primary spermatocytes, Leydig and Sertoli cells of 8, 12 and 17-week-old animals. These results suggest that selenoprotein S may play a role in spermatogenesis.
Notes SpringerLink Date Monday, December 18, 2006
Language eng
Field of Research 111699 Medical Physiology not elsewhere classified
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2006, Springer Science+Business Media B.V.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30007724

Document type: Journal Article
Collection: School of Exercise and Nutrition Sciences
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 3 times in TR Web of Science
Scopus Citation Count Cited 4 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 427 Abstract Views  -  Detailed Statistics
Created: Mon, 29 Sep 2008, 08:55:23 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.