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Prevention of type 2 diabetes by lifestyle intervention in an Australian primary health care setting : Greater Green Triangle (GGT) Diabetes Prevention Project

Laatikainen, Tiina, Dunbar, James, Chapman, Anna, Kilkkinen, Annamari, Vartiainen, Erkki, Heistaro, Sami, Philpot, Ben, Absetz, Pilvikki, Bunker, Stephen, O'Neil, Adrienne, Reddy, Prasuna, Best, James D. and Janus, Edward D. 2007, Prevention of type 2 diabetes by lifestyle intervention in an Australian primary health care setting : Greater Green Triangle (GGT) Diabetes Prevention Project, BMC public health, vol. 7, no. 249, pp. 1-20.

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Title Prevention of type 2 diabetes by lifestyle intervention in an Australian primary health care setting : Greater Green Triangle (GGT) Diabetes Prevention Project
Author(s) Laatikainen, Tiina
Dunbar, James
Chapman, Anna
Kilkkinen, Annamari
Vartiainen, Erkki
Heistaro, Sami
Philpot, Ben
Absetz, Pilvikki
Bunker, Stephen
O'Neil, Adrienne
Reddy, Prasuna
Best, James D.
Janus, Edward D.
Journal name BMC public health
Volume number 7
Issue number 249
Start page 1
End page 20
Publisher BioMed Central Ltd
Place of publication London, England
Publication date 2007-09-19
ISSN 1471-2458
Keyword(s) diabetes
type 2 diabetes
diabetes mellitus
health promotion
lifestyle
Summary Background
Randomised controlled trials demonstrate a 60% reduction in type 2 diabetes incidence through lifestyle modification programmes. The aim of this study is to determine whether such programmes are feasible in primary health care.

Methods
An intervention study including 237 individuals 40–75 years of age with moderate or high risk of developing type 2 diabetes. A structured group programme with six 90 minute sessions delivered during an eight month period by trained nurses in Australian primary health care in 2004–2006. Main outcome measures taken at baseline, three, and 12 months included weight, height, waist circumference, fasting plasma glucose and lipids, plasma glucose two hours after oral glucose challenge, blood pressure, measures of psychological distress and general health outcomes. To test differences between baseline and follow-up, paired t-tests and Wilcoxon rank sum tests were performed.

Results
At twelve months participants' mean weight reduced by 2.52 kg (95% confidence interval 1.85 to 3.19) and waist circumference by 4.17 cm (3.48 to 4.87). Mean fasting glucose reduced by 0.14 mmol/l (0.07 to 0.20), plasma glucose two hours after oral glucose challenge by 0.58 mmol/l (0.36 to 0.79), total cholesterol by 0.29 mmol/l (0.18 to 0.40), low density lipoprotein cholesterol by 0.25 mmol/l (0.16 to 0.34), triglycerides by 0.15 mmol/l (0.05 to 0.24) and diastolic blood pressure by 2.14 mmHg (0.94 to 3.33). Significant improvements were also found in most psychological measures.

Conclusion
This study provides evidence that a type 2 diabetes prevention programme using lifestyle intervention is feasible in primary health care settings, with reductions in risk factors approaching those observed in clinical trials.

Trial Number
Current Controlled Trials ISRCTN38031372
Language eng
Field of Research 111717 Primary Health Care
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2007, Laatikainen et al
Persistent URL http://hdl.handle.net/10536/DRO/DU:30007828

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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.