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Effects of Salvia miltiorrhiza after acute myocardial infarction in rats

Ji, Xin-Yan, Tan, Benny Kwong-Huat, Huang, Shan-Hong, Whiteman, Matthew, Zhu, Yi-Chun, Duan, Wei, Zhu, Yi-Zhun and Linz, Wolfgang 2004, Effects of Salvia miltiorrhiza after acute myocardial infarction in rats, in Novel compounds from natural products in the new millennium, World Scientific, Singapore, pp.183-195.

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Title Effects of Salvia miltiorrhiza after acute myocardial infarction in rats
Formatted title Effects of Salvia miltiorrhiza after acute myocardial infarction in rats
Author(s) Ji, Xin-Yan
Tan, Benny Kwong-Huat
Huang, Shan-Hong
Whiteman, Matthew
Zhu, Yi-Chun
Duan, Wei
Zhu, Yi-Zhun
Linz, Wolfgang
Title of book Novel compounds from natural products in the new millennium
Editor(s) Tan, Benny K-H
Bay, Boon-Huat
Zhu, Yi-Zhun
Publication date 2004
Total chapters 30
Start page 183
End page 195
Total pages 13
Publisher World Scientific
Place of Publication Singapore
Summary Acute myocardial infarction (M!) is the commonest cause of death in the developed countries, and it is on the rise in developing countries. Ramipril is a well-knownAngiotensin-converting enzyme (ACE) inhibitorwhich inhibits conversion ofinactive angiotensin I to active angiotensin II. Experimental studies have shown thatACE inhibitors administered chronicallybefore acuteMImight limitmyocardial infarct size, improve cardiac function and prevent cardiac hypertrophy [1, 2]. The Chinese herb, Salvia miltiorrhiza (SM), has been widely and successfully usedmainly for anginapectoris,MI and stroke [3]. Compared to ramipril, however, there is very limited biochemical information availableto demonstrate themechanismsofSMs
cardio-protective effects. This study thus investigates the possible
biochemical and molecularmechanisms ofsuch effects ofSMin Wistar rats in comparison with those oframipril.
ISBN 9812561137
9789812561138
Language eng
Field of Research 111502 Clinical Pharmacology and Therapeutics
HERDC Research category B1.1 Book chapter
Copyright notice ©2004, World Scientific
Persistent URL http://hdl.handle.net/10536/DRO/DU:30008346

Document type: Book Chapter
Collection: School of Medicine
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