Effect of sodium bicarbonate on muscle metabolism during intense endurance cycling

Stephens, Terry, McKenna, Michael, Canny, Benedict, Snow, Rodney and McConell, Glenn 2002, Effect of sodium bicarbonate on muscle metabolism during intense endurance cycling, Medicine and Science in Sports and Exercise, vol. 34, no. 4, pp. 614-621.

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Title Effect of sodium bicarbonate on muscle metabolism during intense endurance cycling
Author(s) Stephens, Terry
McKenna, Michael
Canny, Benedict
Snow, Rodney
McConell, Glenn
Journal name Medicine and Science in Sports and Exercise
Volume number 34
Issue number 4
Start page 614
End page 621
Publisher American College of Sports Medicine
Place of publication Madison, Wis.
Publication date 2002-04
ISSN 0195-9131
1530-0315
Keyword(s) metabolic alkalosis
muscle glycogen
muscle and blood lactate
[H+]
acid-base
intense exercise
Summary Introduction: Sodium bicarbonate (NaHCO3) ingestion has been shown to increase both muscle glycogenolysis and glycolysis during brief submaximal exercise. These changes may be detrimental to performance during more prolonged, exhaustive exercise. This study examined the effect of NaHCO3 ingestion on muscle metabolism and performance during intense endurance exercise of ~60 min in seven endurance-trained men. Methods: Subjects ingested 0.3 g·kg-1 body mass of either NaHCO3 or CaCO3 (CON) 2 h before performing 30 min of cycling exercise at 77 ± 1% [latin capital V with dot above]O2peak followed by completion of 469 ± 21 kJ as quickly as possible (~30 min, ~80% [latin capital V with dot above]O2peak). Results: Immediately before, and throughout exercise, arterialized-venous plasma HCO3- concentrations were higher (P < 0.05) whereas plasma and muscle H+ concentrations were lower (P < 0.05) in NaHCO3 compared with CON. Blood lactate concentrations were higher (P < 0.05) during exercise in NaHCO3, but there was no difference between trials in muscle glycogen utilization or muscle lactate content during exercise. Reductions in PCr and ATP and increases in muscle Cr during exercise were also unaffected by NaHCO3 ingestion. Accordingly, exercise performance time was not different between treatments. Conclusion: NaHCO3 ingestion resulted in a small muscle alkalosis but had no effect on muscle metabolism or intense endurance exercise performance in well-trained men.
Language eng
Field of Research 060104 Cell Metabolism
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2002, American College of Sports Medicine
Persistent URL http://hdl.handle.net/10536/DRO/DU:30008516

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