Adaptations to short-term high-fat diet persist during exercise despite high carbohydrate availability

Burke, Louise M., Hawley, John A., Angus, Damien, Cox, Gregory, Clark, Sally A., Cummings, Nicola K., Desbrow, Ben and Hargreaves, Mark 2002, Adaptations to short-term high-fat diet persist during exercise despite high carbohydrate availability, Medicine and science in sports and exercise, vol. 34, no. 1, pp. 83-91.

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Title Adaptations to short-term high-fat diet persist during exercise despite high carbohydrate availability
Author(s) Burke, Louise M.
Hawley, John A.
Angus, Damien
Cox, Gregory
Clark, Sally A.
Cummings, Nicola K.
Desbrow, Ben
Hargreaves, Mark
Journal name Medicine and science in sports and exercise
Volume number 34
Issue number 1
Start page 83
End page 91
Total pages 9 p.
Publisher Lippincott Williams and Wilkins
Place of publication Philadelphia, Pa.
Publication date 2002-01
ISSN 0195-9131
Summary Purpose: Five days of a high-fat diet produce metabolic adaptations that increase the rate of fat oxidation during prolonged exercise. We investigated whether enhanced rates of fat oxidation during submaximal exercise after 5 d of a high-fat diet would persist in the face of increased carbohydrate (CHO) availability before and during exercise.

Methods: Eight well-trained subjects consumed either a high-CHO (9.3 g·kg-1·d-1 CHO, 1.1 g·kg-1·d-1 fat; HCHO) or an isoenergetic high-fat diet (2.5 g·kg-1·d-1 CHO, 4.3 g·kg-1·d-1 fat; FAT-adapt) for 5 d followed by a high-CHO diet and rest on day 6. On day 7, performance testing (2 h steady-state (SS) cycling at 70% peak O2 uptake [[latin capital V with dot above]O2peak] + time trial [TT]) of 7 kJ·kg-1) was undertaken after a CHO breakfast (CHO 2 g·kg-1) and intake of CHO during cycling (0.8 g·kg-1·h-1).

Results: FAT-adapt reduced respiratory exchange ratio (RER) values before and during cycling at 70% [latin capital V with dot above]O2peak; RER was restored by 1 d CHO and CHO intake during cycling (0.90 ± 0.01, 0.80 ± 0.01, 0.91 ± 0.01, for days 1, 6, and 7, respectively). RER values were higher with HCHO (0.90 ± 0.01, 0.88 ± 0.01 (HCHO > FAT-adapt, P < 0.05), 0.95 ± 0.01 (HCHO > FAT-adapt, P < 0.05)). On day 7, fat oxidation remained elevated (73 ± 4 g vs 45 ± 3 g, P < 0.05), whereas CHO oxidation was reduced (354 ± 11 g vs 419 ± 13 g, P < 0.05) throughout SS in FAT-adapt versus HCHO. TT performance was similar for both trials (25.53 ± 0.67 min vs 25.45 ± 0.96 min, NS).

Conclusion: Adaptations to a short-term high-fat diet persisted in the face of high CHO availability before and during exercise, but failed to confer a performance advantage during a TT lasting ~ 25 min undertaken after 2 h of submaximal cycling.
Notes External
Language eng
Field of Research 110602 Exercise Physiology
HERDC Research category C1 Refereed article in a scholarly journal
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Document type: Journal Article
Collection: School of Health Sciences
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