Single vs. two steroid injections for carpal tunnel syndrome: a randomised clinical trial

Wong, S., Hui, A., Lo, Sing Kai, Chui, J., Poon, W. and Wong, L. 2005, Single vs. two steroid injections for carpal tunnel syndrome: a randomised clinical trial, International journal of clinical practice, vol. 59, no. 12, pp. 1417-1421.

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Title Single vs. two steroid injections for carpal tunnel syndrome: a randomised clinical trial
Author(s) Wong, S.
Hui, A.
Lo, Sing Kai
Chui, J.
Poon, W.
Wong, L.
Journal name International journal of clinical practice
Volume number 59
Issue number 12
Start page 1417
End page 1421
Publisher Blackwell Publishing Ltd.
Place of publication Abingdon, England
Publication date 2005-11
ISSN 1368-5031
1742-1241
Keyword(s) carpal tunnel syndrome
steroid injection
randomised controlled trial
Summary We investigated the efficacy of a single vs. double steroid injections in the treatment of carpal tunnel syndrome (CTS) in a randomised double-blind controlled trial. Patients with idiopathic CTS were randomised into (i) one group receiving a baseline methylprednisolone acetate injection plus a saline injection 8 weeks later and (ii) a second group receiving methylprednisolone acetate injection at baseline and at 8 weeks. The primary outcome was the Global Symptom Score (GSS). Forty patients were recruited. By 40 weeks, the mean GSS improved from 25.6 to 14.1 in the single-injection group whereas from 26.7 to 12.6 in the reinjection group, but there was no significant difference in GSS between the two groups (p = 0.26). There were also no significant differences in terms of electrophysiological and functional outcomes. The results suggest that an additional steroid injection confers no added benefit to a single injection in terms of symptom relief.
Language eng
Field of Research 119999 Medical and Health Sciences not elsewhere classified
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2005, Blackwell Publishing Ltd
Persistent URL http://hdl.handle.net/10536/DRO/DU:30009335

Document type: Journal Article
Collection: School of Psychology
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