The Jak-Stat pathway in Hematopoiesis and Disease

Ward, Alister 2002, The Jak-Stat pathway in Hematopoiesis and Disease, Kluwer / Springer, New York, N.Y..

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Title The Jak-Stat pathway in Hematopoiesis and Disease
Author(s) Ward, Alister
Editor(s) Ward, Alister
Publication date 2002
Series Molecular biology intelligence unit ; 20
Total pages 140 p.
Publisher Kluwer / Springer
Place of Publication New York, N.Y.
Keyword(s) Hematopoiesis -- Regulation
Cytokines -- Receptors
Hematopoiesis -- physiology
Cytokines -- physiology
Leukemia -- physiopathology
Receptors, Cytokine -- physiology
Signal Transduction
Summary This book for the first time comprehensively surveys the research investigating the Jak-Stat pathway and its role in normal blood development as well as its perturbation in disease. It draws on the expertise of world-renowned medical researchers to take the reader from basic biology through to recent therapeutic advances.
Notes Contents: Jaks and normal hematopoiesis -- Jak3-dependent pathways in hematopoiesis and SCID -- Stat activation by Src, Fes and Btk tyrosine kinases -- Stats and hematopoiesis --Stat signaling in leukemia: implications for pathogenesis and treatment -- The role of the Jak-Stat pathway in hematopoiesis and immune responses in Drosophila -- SOCS proteins in hematopoiesis.
ISBN 0306474247
9780306474248
Language eng
Field of Research 060111 Signal Transduction
Socio Economic Objective 970106 Expanding Knowledge in the Biological Sciences
HERDC Research category A7 Edited book
Persistent URL http://hdl.handle.net/10536/DRO/DU:30010154

Document type: Book
Collection: School of Biological and Chemical Sciences
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