The Jak-Stat pathway in Hematopoiesis and Disease

2002, The Jak-Stat pathway in Hematopoiesis and Disease. Edited by Ward, Alister, Kluwer / Springer, New York, N.Y..

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Title The Jak-Stat pathway in Hematopoiesis and Disease
Editor(s) Ward, AlisterORCID iD for Ward, Alister
Publication date 2002
Series Molecular biology intelligence unit ; 20
Total pages 140 p.
Publisher Kluwer / Springer
Place of Publication New York, N.Y.
Keyword(s) Hematopoiesis -- Regulation
Cytokines -- Receptors
Hematopoiesis -- physiology
Cytokines -- physiology
Leukemia -- physiopathology
Receptors, Cytokine -- physiology
Signal Transduction
Summary This book for the first time comprehensively surveys the research investigating the Jak-Stat pathway and its role in normal blood development as well as its perturbation in disease. It draws on the expertise of world-renowned medical researchers to take the reader from basic biology through to recent therapeutic advances.
Notes Contents: Jaks and normal hematopoiesis -- Jak3-dependent pathways in hematopoiesis and SCID -- Stat activation by Src, Fes and Btk tyrosine kinases -- Stats and hematopoiesis --Stat signaling in leukemia: implications for pathogenesis and treatment -- The role of the Jak-Stat pathway in hematopoiesis and immune responses in Drosophila -- SOCS proteins in hematopoiesis.
ISBN 0306474247
Language eng
Field of Research 060111 Signal Transduction
Socio Economic Objective 970106 Expanding Knowledge in the Biological Sciences
HERDC Research category A7 Edited book
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Document type: Book
Collection: School of Biological and Chemical Sciences
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