Peripheral quantitative computed tomography in children and adolescents : the 2007 ISCD pediatric official positions

Zemel, Babette, Bass, Shona, Binkley, Theresa, Ducher, Gaele, Macdonald, Heather, McKay, Heather, Moyer-Mileur, Laurie, Shepherd, John, Specker, Bonny, Ward, Kate and Hans, Didier 2008, Peripheral quantitative computed tomography in children and adolescents : the 2007 ISCD pediatric official positions, Journal of clinical densitometry, vol. 11, no. 1, pp. 59-74, doi: 10.1016/j.jocd.2007.12.006.

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Title Peripheral quantitative computed tomography in children and adolescents : the 2007 ISCD pediatric official positions
Author(s) Zemel, Babette
Bass, Shona
Binkley, Theresa
Ducher, Gaele
Macdonald, Heather
McKay, Heather
Moyer-Mileur, Laurie
Shepherd, John
Specker, Bonny
Ward, Kate
Hans, Didier
Journal name Journal of clinical densitometry
Volume number 11
Issue number 1
Start page 59
End page 74
Publisher Elsevier B.V.
Place of publication Amsterdam, The Netherlands
Publication date 2008-01
ISSN 1094-6950
Keyword(s) bone mineral density
peripheral quantitative computed tomography
Summary Peripheral quantitative computed tomography (pQCT) has mainly been used as a research tool in children. To evaluate the clinical utility of pQCT and formulate recommendations for its use in children, the International Society
of Clinical Densitometry (ISCD) convened a task force to review the literature and propose areas of consensus and future research. The types of pQCT technology available, the clinical application of pQCT for bone health assessment in children, the important elements to be included in a pQCT report, and quality control monitoring techniques were evaluated. The review revealed a lack of standardization of pQCT techniques, and a paucity of data regarding differences between pQCT manufacturers, models and software versions and their impact in pediatric assessment. Measurement sites varied across studies. Adequate reference data, a critical element for interpretation of pQCT results, were entirely lacking, although some comparative data on healthy children were available. The elements of the
pQCT clinical report and quality control procedures are similar to those recommended for dual-energy X-ray absorptiometry. Future research is needed to establish evidence-based criteria for the selection of the measurement site, scan acquisition and analysis parameters, and outcome measures. Reference data that sufficiently characterize the normal range of variability in the population also need to be established.
Language eng
DOI 10.1016/j.jocd.2007.12.006
Field of Research 111403 Paediatrics
HERDC Research category C1 Refereed article in a scholarly journal
HERDC collection year 2008
Copyright notice ©2008, The International Society for Clinical Densitometry
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Document type: Journal Article
Collections: Faculty of Health
School of Exercise and Nutrition Sciences
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