In vitro bioactivity evaluation of titanium and niobium metals with different surface morphologies

Wang, X. J., Li, Y. C., Lin, J. G., Yamada, Y., Hodgson, P. D. and Wen, C. E. 2008, In vitro bioactivity evaluation of titanium and niobium metals with different surface morphologies, Acta biomaterialia, vol. 4, no. 5, pp. 1530-1535, doi: 10.1016/j.actbio.2008.04.005.

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Title In vitro bioactivity evaluation of titanium and niobium metals with different surface morphologies
Author(s) Wang, X. J.
Li, Y. C.
Lin, J. G.
Yamada, Y.
Hodgson, P. D.
Wen, C. E.
Journal name Acta biomaterialia
Volume number 4
Issue number 5
Start page 1530
End page 1535
Total pages 6
Publisher Elsevier B.V.
Place of publication Amsterdam, The Netherlands
Publication date 2008-09
ISSN 1742-7061
Keyword(s) bioactivity
Simulated body fluid (SBF)
Summary Current orthopaedic biomaterials research mainly focuses on designing implants that could induce controlled, guided and rapid healing. In the present study, the surface morphologies of titanium (Ti) and niobium (Nb) metals were tailored to form nanoporous, nanoplate and nanofibre-like structures through adjustment of the temperature in the alkali-heat treatment. The in vitro bioactivity of these structures was then evaluated by soaking the treated samples in simulated body fluid (SBF). It was found that the morphology of the modified surface significantly influenced the apatite-inducing ability. The Ti surface with a nanofibre-like structure showed better apatite-inducing ability than the nanoporous or nanoplate surface structures. A thick dense apatite layer formed on the Ti surface with nanofibre-like structure after 1 week of soaking in SBF. It is expected that the nanofibre-like surface could achieve good apatite formation in vivo and subsequently enhance osteoblast cell adhesion and bone formation.
Language eng
DOI 10.1016/j.actbio.2008.04.005
Field of Research 090301 Biomaterials
Socio Economic Objective 970109 Expanding Knowledge in Engineering
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2008, Elsevier B.V.
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Document type: Journal Article
Collections: Centre for Material and Fibre Innovation
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