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Preventing the onset of depressive disorders : a meta-analytic review of psychological interventions Cuijpers, Pim, van Straten, Annemieke, Smit, Filip, Mihalopoulos, Cathrine and Beekman, Aartjan 2008, Preventing the onset of depressive disorders : a meta-analytic review of psychological interventions, American journal of psychiatry, vol. 165, pp. 1272-1280. Title Preventing the onset of depressive disorders : a meta-analytic review of psychological interventions Author(s) Cuijpers, Pim van Straten, Annemieke Smit, Filip Mihalopoulos, Cathrine Beekman, Aartjan Journal name American journal of psychiatry Volume number 165 Start page 1272 End page 1280 Publisher American Psychiatric Publishing Place of publication Baltimore, Md. Publication date 2008 ISSN 0002-953X 1535-7228 1139-3475 Summary OBJECTIVE: A growing number of studies have tested the efficacy of preventive interventions in reducing the incidence of depressive disorders. Until now, no meta-analysis has integrated the results of these studies. METHOD: The authors conducted a meta-analysis. After a comprehensive literature search, 19 studies were identified that met inclusion criteria. The studies had to be randomized controlled studies in which the incidence of depressive disorders (based on diagnostic criteria) in an experimental group could be compared with that of a control group. RESULTS: The mean incidence rate ratio was 0.78, indicating a reduction of the incidence of depressive disorders by 22% in experimental compared with control groups. Heterogeneity was low to moderate (I2=33%). The number needed to treat to prevent one case of depressive disorder was 22. Moderator analyses revealed no systematic differences between target populations or types of prevention (universal, selective, or indicated). The data included indications that prevention based on interpersonal psychotherapy may be more effective than prevention based on cognitive-behavioral therapy. CONCLUSIONS: Prevention of new cases of depressive disorders does seem to be possible. Prevention may become an important way, in addition to treatment, to reduce the enormous public health burden of depression in the coming years. Language eng Field of Research 111716 Preventive Medicine Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences HERDC Research category C1 Refereed article in a scholarly journal HERDC collection year 2008 Copyright notice ©2008 American Psychiatric Association Persistent URL http://hdl.handle.net/10536/DRO/DU:30017369 Document type: Journal Article Collection: Public Health Research, Evaluation, and Policy Cluster Related Links Link Description Connect to published version (restricted access) Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Fri, 14 Aug 2009, 13:52:35 EST Tue, 17 Nov 2009, 15:08:52 EST Wed, 18 Nov 2009, 08:22:38 EST Wed, 18 Nov 2009, 08:23:29 EST Wed, 18 Nov 2009, 08:28:20 EST Wed, 11 Aug 2010, 12:05:16 EST Mon, 15 Apr 2013, 11:20:33 EST Mon, 15 Apr 2013, 11:21:08 EST Filtered Full Citation counts:   Cited 89 times in TR Web of Science Cited 107 times in Scopus Search Google Scholar Access Statistics: 313 Abstract Views  -  Detailed Statistics Created: Fri, 14 Aug 2009, 13:52:35 EST

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