Low-intensity pulsed ultrasound for chronic patellar tendinopathy : a randomized, double-blind, placebo-controlled trial

Warden, S. J., Metcalf, B. R., Kiss, Z. S., Cook, J. L., Purdam, C. R., Bennell, K. L. and Crossley, K. M. 2008, Low-intensity pulsed ultrasound for chronic patellar tendinopathy : a randomized, double-blind, placebo-controlled trial, Rheumatology, vol. 47, no. 4, pp. 467-471.

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Title Low-intensity pulsed ultrasound for chronic patellar tendinopathy : a randomized, double-blind, placebo-controlled trial
Author(s) Warden, S. J.
Metcalf, B. R.
Kiss, Z. S.
Cook, J. L.
Purdam, C. R.
Bennell, K. L.
Crossley, K. M.
Journal name Rheumatology
Volume number 47
Issue number 4
Start page 467
End page 471
Publisher Oxford University Press
Place of publication Oxford, England
Publication date 2008-04
ISSN 1462-0324
1462-0332
Keyword(s) anterior knee pain
jumper's knee
randomized controlled trial
sports medicine
tendinitis
tendinosis
Summary Objective. Patellar tendinopathy (PT) is a common and significant clinical condition for which there are few established interventions. One intervention that is currently being used clinically to manage PT symptoms is the introduction of low-intensity pulsed ultrasound (LIPUS). The aim of this study was to investigate the clinical efficacy of LIPUS in the management of PT symptoms.

Methods. A randomized, double-blind, placebo-controlled study was conducted. Volunteers with clinically and radiologically confirmed PT were randomly allocated to either an active-LIPUS (treatment) or inactive-LIPUS (placebo) group. LIPUS was self-administered by participants for 20 min/day, 7 days/week for 12 weeks. All participants also completed a daily, standardized eccentric exercise programme based on best practice. Primary outcomes were change in pain during the participant's most aggravating activity in the preceding week, measured on 10 cm visual analogue scales for both usual (VAS-U) and worst (VAS-W) tendon pain.

Results. Out of 156 individuals who volunteered, 37 met the eligibility criteria and were randomized to either active-LIPUS (n = 17) or inactive-LIPUS (n = 20). Using an intention-to-treat analysis, VAS-U and VAS-W for the entire cohort decreased by 1.6 ± 1.9 cm (P < 0.01) and 2.5 ± 2.4 cm (P < 0.01), respectively. There were no differences between the active- and inactive-LIPUS groups for change in VAS-U (–0.2 cm; 95% CI, –1.5, 1.1 cm) (P = 0.74) or VAS-W (–0.5 cm; 95% CI, –2.1, 1.1 cm) (P = 0.57). A per-protocol analysis provided similar results.

Conclusions.
These findings suggest that LIPUS does not provide any additional benefit over and above placebo in the management of symptoms associated with PT.
Language eng
Field of Research 110399 Clinical Sciences not elsewhere classified
HERDC Research category C1 Refereed article in a scholarly journal
HERDC collection year 2008
Copyright notice ©2008, The Authors
Persistent URL http://hdl.handle.net/10536/DRO/DU:30017474

Document type: Journal Article
Collection: School of Exercise and Nutrition Sciences
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