Fatty acid composition in tissues of mice fed diets containing conjugated linolenic acid and conjugated linoleic acid

Yuan, Gao-Feng, Sinclair, Andrew J, Sun, Hai-Yan and Li, Duo 2009, Fatty acid composition in tissues of mice fed diets containing conjugated linolenic acid and conjugated linoleic acid, Journal of food lipids, vol. 16, no. 2, pp. 148-163.

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Title Fatty acid composition in tissues of mice fed diets containing conjugated linolenic acid and conjugated linoleic acid
Author(s) Yuan, Gao-Feng
Sinclair, Andrew J
Sun, Hai-Yan
Li, Duo
Journal name Journal of food lipids
Volume number 16
Issue number 2
Start page 148
End page 163
Publisher Wiley-Blackwell Publishing
Place of publication Oxford, England
Publication date 2009-05
ISSN 1065-7258
1745-4522
Summary The influence of 1% alpha-eleostearic acid (α-ESA, cis9,trans11,trans 13-18:3) and 1% punicic acid (PA, cis9,trans11,cis13-18:3) on fatty acid composition in mouse tissues was compared with conjugated linoleic acid (CLA, mixture of primarily cis9,trans11- and trans10,cis12-18:2) in the present study. The content (% total fatty acids) of 18:2n-6 was significantly reduced in the heart and adipose tissues, and total polyunsaturated fatty acids (PUFAs) and n-6 PUFA were significantly reduced in adipose tissue by α-ESA, PA and CLA feeding. The content of 22:6n-3 and total n-3 PUFA were significantly increased in the liver, kidney and heart by PA feeding, but not by α-ESA. In contrast to PA, supplementation with CLA significantly decreased 22:6n-3 in the liver, kidney and heart. The content of 20:4n-6 was significantly decreased in the liver and kidney by CLA feeding, but not by α-ESA and PA. The present results indicate that α-ESA, PA and CLA have differential effects on 22:6n-3 and 20:4n-6 content in mouse tissues.
Language eng
Field of Research 110107 Metabolic Medicine
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
HERDC collection year 2009
Copyright notice ©2009, Wiley Periodicals, Inc.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30019526

Document type: Journal Article
Collection: School of Exercise and Nutrition Sciences
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