A brief introduction to the history of the ß-amyloid protein (Aß) of Alzheimer's disease
Small, David H. and Barrow, Colin J. 2006, A brief introduction to the history of the ß-amyloid protein (Aß) of Alzheimer's disease, in Abeta peptide and Alzheimer's disease : celebrating a century of research, Springer, London, pp.1-4.
Title
A brief introduction to the history of the ß-amyloid protein (Aß) of Alzheimer's disease
Abeta peptide and Alzheimer's disease : celebrating a century of research
Editor(s)
Barrow, Colin Small, David
Publication date
2006
Chapter number
1
Total chapters
16
Start page
1
End page
4
Total pages
4
Publisher
Springer
Place of Publication
London
Summary
Alzheimer’s disease (AD) is the most common cause of dementia in the elderly. Typically, the disease progresses in a prolonged, inexorable manner [1]. Patients initially show symptoms of mild cognitive impairment, which may include some memory loss. As the disease progresses, more severe memory loss occurs (e.g., retrograde amnesia) leading to confusion and lack of orientation. The patient is often institutionalized in this period, as it becomes increasingly difficult for family members to cope with the constant requirements of care. In later stages of the disease, apathy and stupor can occur, and the patient becomes bedridden.
ISBN
1846284406 1852339616 9781846284403 9781852339616
Language
eng
Field of Research
119999 Medical and Health Sciences not elsewhere classified