Association between impaired glucose metabolism and quality of life

Tapp, Robyn J., Dunstan, David W., Phillips, Pat, Tonkin, Andrew, Zimmet, Paul Z. and Shaw, Jonathan E. 2006, Association between impaired glucose metabolism and quality of life, Diabetes research and clinical practice, vol. 74, no. 2, pp. 154-161.


Title Association between impaired glucose metabolism and quality of life
Author(s) Tapp, Robyn J.
Dunstan, David W.
Phillips, Pat
Tonkin, Andrew
Zimmet, Paul Z.
Shaw, Jonathan E.
Journal name Diabetes research and clinical practice
Volume number 74
Issue number 2
Start page 154
End page 161
Publisher Elsevier Science
Place of publication Amsterdam, Netherlands
Publication date 2006-11
ISSN 0168-8227
1872-8227
Keyword(s) quality of life
glucose tolerance status
diabetes mellitus
complications
Summary Aims
We examined the association of quality of life with glucose tolerance status in an Australian population to determine the stage in the development of diabetes that quality of life is impaired.

Methods
The Australian Diabetes, Obesity and Lifestyle study (AusDiab) was a population-based study of 11,247 people from randomly selected areas of Australia. As part of the study, participants underwent an oral glucose tolerance test and completed the SF-36 quality of life questionnaire.

Results
Previously diagnosed diabetes was associated with a significantly greater risk of being in the lowest quartile of each dimension of the SF-36 scale (except for mental health) and this association was only partially attenuated by adjustment for age, sex, body mass index (BMI), physical activity and treatment for hypertension and lipid abnormalities (adjusted odds ratios [95% CI]: bodily pain, 1.51 [1.18–1.94]; general health, 2.20 [1.64–2.95]; physical functioning, 1.50 [1.10–2.05]; role limitation (emotional), 1.43 [1.07–1.91]; role limitation (physical), 1.57 [1.13–2.18]; social functioning, 1.93 [1.46–2.54] and vitality, 2.24 [1.56–3.22]. Among those with newly diagnosed diabetes (NDM) and impaired glucose tolerance (IGT), there was also evidence of reduced quality of life on some dimensions of the SF-36 scale (NDM, general health, physical functioning and role limitation (physical); IGT, physical functioning and social functioning) after adjustment for confounders.

Conclusion
These findings show that diabetes is associated with a reduced quality of life and that this is evident in the early stage of the disease, particularly in relation to the ability to perform physical activities.
Language eng
Field of Research 111199 Nutrition and Dietetics not elsewhere classified
HERDC Research category C1.1 Refereed article in a scholarly journal
ERA Research output type C Journal article
Copyright notice ©2006, Elsevier Ireland
Persistent URL http://hdl.handle.net/10536/DRO/DU:30020828

Document type: Journal Article
Collection: School of Exercise and Nutrition Sciences
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