Aptasensors design considerations Lim, Y. C., Kouzani, A. Z. and Duan, W. 2009, Aptasensors design considerations. In Cai, Zhihua, Li, Zhenhua, Kang, Zhuo and Liu, Yong (ed), Computational intelligence and intelligent systems, Springer, Berlin, Germany, pp.118-127, doi: 10.1007/978-3-642-04962-0_14. Attached Files Name Description MIMEType Size Downloads Title Aptasensors design considerations Author(s) Lim, Y. C. Kouzani, A. Z. orcid.org/0000-0002-6292-1214 Duan, W. orcid.org/0000-0001-5782-9184 Title of book Computational intelligence and intelligent systems Editor(s) Cai, Zhihua Li, Zhenhua Kang, Zhuo Liu, Yong Publication date 2009 Series Communications in computer and information science ; volume 51 Chapter number 14 Total chapters 54 Start page 118 End page 127 Total pages 10 Publisher Springer Place of Publication Berlin, Germany Keyword(s) aptamer immobilization aptasensor Summary With the advancement of biotechnology, aptamer-based sensors have received intense attention in both research and commercial worlds. This is driven by the advantages of small molecule size, chemical stability, and cost effectiveness of aptamers over the conventional analyte detection using antibodies. This paper explores the aptasensors from a designer perspective and discusses the aptasensor design considerations by giving an overview of surface functionalization techniques and the existing mechanisms used to detect biomolecular interactions. It also expounds the factors that influence the accuracy and sensitivity of aptasensors. ISBN 9783642049613 3642049613 ISSN 1865-0929 1865-0937 Language eng DOI 10.1007/978-3-642-04962-0_14 Field of Research 091306 Microelectromechanical Systems (MEMS) 100402 Medical Biotechnology Diagnostics (incl Biosensors) Socio Economic Objective 920203 Diagnostic Methods HERDC Research category B1 Book chapter Copyright notice ©2009, Springer-Verlag Persistent URL http://hdl.handle.net/10536/DRO/DU:30022918 Document type: Book Chapter Collections: School of Medicine School of Engineering Related Links Link Description Connect to published version Go to link with your DU access privileges     Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved. Versions Version Filter Type Fri, 05 Feb 2010, 10:22:39 EST Fri, 05 Feb 2010, 10:24:01 EST Mon, 08 Feb 2010, 08:17:42 EST Mon, 08 Feb 2010, 08:19:16 EST Thu, 04 Mar 2010, 13:25:07 EST Fri, 11 Jun 2010, 17:19:19 EST Fri, 17 Feb 2012, 13:10:33 EST Thu, 12 Sep 2013, 15:52:16 EST Wed, 02 Jul 2014, 15:05:52 EST Mon, 21 Jul 2014, 09:58:27 EST Thu, 20 Nov 2014, 13:47:58 EST Mon, 19 Jan 2015, 11:02:17 EST Fri, 06 Feb 2015, 10:32:51 EST Filtered Full Citation counts:   Cited 4 times in TR Web of Science Cited 5 times in Scopus Search Google Scholar Access Statistics: 747 Abstract Views, 5 File Downloads  -  Detailed Statistics Created: Fri, 05 Feb 2010, 10:22:38 EST by Abbas Kouzani

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