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Potential antiarrhythmic and cardioprotective agents based on adenosine

Wright, Denis Matthew John. 1999, Potential antiarrhythmic and cardioprotective agents based on adenosine, Ph.D. thesis, School of Biological and Chemical Sciences, Deakin University.

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Title Potential antiarrhythmic and cardioprotective agents based on adenosine
Author Wright, Denis Matthew John.
Institution Deakin University
School School of Biological and Chemical Sciences
Faculty Faculty of Science and Technology
Degree name Ph.D.
Date submitted 1999
Keyword(s) Adenosine - Receptors
Adenosine - Metabolism
Summary Adenosine is an endogenous ligand which is involved in a large number of physiological processes. Intravenous treatment of animals with adenoisine, which is quickly metabolised, has the effect of temporarily lowering the heart-rate. Several highly potent compounds more resistent to metabolic degradation were synthesised. The second part of the project involved synthesis of compounds which were hopefully selective for the A3 adenoisine receptor which has the most limited tissue distribution within the body and is thought to be involved in a number of pathological processes including asthma.
Language eng
Description of original viii, 171 leaves : ill. ; 30 cm.
Dewey Decimal Classification 572.425
Persistent URL http://hdl.handle.net/10536/DRO/DU:30023463

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Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.