A cetylcholinesterase is increased in mouse neuronal and astrocyte cultures after treatment with b-amyloid peptides

Sáez-Valero, Javier, Fodero, Lisa R., White, Anthony R., Barrow, Colin J. and Small, David H. 2003, A cetylcholinesterase is increased in mouse neuronal and astrocyte cultures after treatment with b-amyloid peptides, Brain Research, vol. 965, no. 1-2, pp. 283-286.

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Title A cetylcholinesterase is increased in mouse neuronal and astrocyte cultures after treatment with b-amyloid peptides
Author(s) Sáez-Valero, Javier
Fodero, Lisa R.
White, Anthony R.
Barrow, Colin J.
Small, David H.
Journal name Brain Research
Volume number 965
Issue number 1-2
Start page 283
End page 286
Publisher Elesvier
Place of publication Amsterdam, Netherlands
Publication date 2003-03
ISSN 0006-8993
1872-6240
Summary The cellular origin of the acetylcholinesterase (AChE) associated with amyloid plaques in the Alzheimer’s disease (AD) brain is unknown. In this study we report that amyloid β-peptides (Aβ) increased AChE levels in both neuronal and astrocytic primary cultures, supporting the possibility that both neurons and glia may make a direct contribution to the pool of AChE seen around amyloid deposits in the AD brain.
Language eng
Field of Research 110999 Neurosciences not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2002, Elsevier Science B.V.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30023810

Document type: Journal Article
Collection: School of Life and Environmental Sciences
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