An anti-hypertensive fish protein hydrolysate is provided, wherein the fish is of the genus Salmo or Oncorhynchus, and wherein the fish protein hydrolysate comprises at least 1 peptide selected from the group consisting of: Leu-Ala-Phe, Leu-Tbr-Phe, Ile-Ile-Phe, Leu-Ala-Tyr, Ile-Ala-Tyr, ValPhe- Tyr, Tyr-Ala-Tyr, Val-Leu-Trp, Ile-Ala-Trp, Tyr-AlaLeu and Tyr-Asn-Arg. Methods of making and methods for using such fish protein hydrolysates are also provided. The invention concerns an anti-hypertensive composition, a method of producing such composition and a dietary supplement made by way of such a method.
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