Ecological and life-history factors influencing the evolution of maternal antibody allocation : a phylogenetic comparison
Addison, BriAnne, Klasing, Kirk C., Robinson, W. Douglas, Austin, Suzanne H. and Ricklefs, Robert E. 2009, Ecological and life-history factors influencing the evolution of maternal antibody allocation : a phylogenetic comparison, Proceedings of the Royal Society B-biological sciences, vol. 276, no. 1675, pp. 3979-3987, doi: 10.1098/rspb.2009.1296.
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Title
Ecological and life-history factors influencing the evolution of maternal antibody allocation : a phylogenetic comparison
Proceedings of the Royal Society B-biological sciences
Volume number
276
Issue number
1675
Start page
3979
End page
3987
Publisher
The Royal Society
Place of publication
London, England
Publication date
2009-11-22
ISSN
0962-8452 1471-2954
Summary
Maternally derived yolk antibodies provide neonates with immune protection in early life at negligible cost to mothers. However, developmental effects on the neonate's future immunity are potentially costly and thus could limit yolk antibody deposition. The benefits to neonatal immunity must be balanced against costs, which may depend on neonate vulnerability to pathogens, developmental trajectories and the immunological strategies best suited to a species' pace of life. We measured yolk antibodies and life-history features of 23 species of small Neotropical birds and assessed the evidence for each of several hypotheses for life history and ecological effects on the evolution of yolk antibody levels. Developmental period and yolk antibodies are negatively related, which possibly reflect the importance of humoral immune priming through antigen exposure, and selection to avoid autoimmunity, in species with a slower pace of life. There is also a strong relationship between body size and yolk antibody concentration, suggesting that larger species are architecturally equipped to produce and transfer higher concentrations of antibodies. These results suggest that developmental effects of maternally derived antibodies, such as imprinting effects on B-cell diversity or autoimmune effects, are important and deserve more consideration in future research.
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