Design and simulation of an interdigital-chaotic advection micromixer for lab-on-a-chip applications

Khoshmanesh, Khashayar, Kouzani, Abbas Z., Nahavandi, Saeid, Baratchi, Sara and Kanwar, Jagat 2009, Design and simulation of an interdigital-chaotic advection micromixer for lab-on-a-chip applications, La houille blanche, vol. 6, pp. 118-124, doi: 10.1051/lhb/2009088.

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Title Design and simulation of an interdigital-chaotic advection micromixer for lab-on-a-chip applications
Author(s) Khoshmanesh, Khashayar
Kouzani, Abbas Z.ORCID iD for Kouzani, Abbas Z. orcid.org/0000-0002-6292-1214
Nahavandi, SaeidORCID iD for Nahavandi, Saeid orcid.org/0000-0002-0360-5270
Baratchi, Sara
Kanwar, JagatORCID iD for Kanwar, Jagat orcid.org/0000-0003-3728-9568
Journal name La houille blanche
Volume number 6
Start page 118
End page 124
Total pages 7
Publisher Revue Generale de l'Electricite
Place of publication Paris, France
Publication date 2009-12
ISSN 0018-6368
1958-5551
Keyword(s) micromixer
microchannel
interdigital
chaotic advection
lab-on-a-chip
Summary The paper presents the design and simulation of a novel passive micromixer. The micromixer consists of two inlet tanks, one mixing channel and two outlet channels. In order to maximise the mixing efficiency, the following considerations are made : (i) The inlet tanks are followed by a series of microchannels, in which the flow is split. The microchannels are arranged in an interdigital manner to  maximise the contact area between the two flows. (ii) The microchannels attached to the lower inlet tank have an upward slope while those attached to the upper tank have a downward slope. The higher-density flow is fed to the lower inlet tank and gets an upward velocity before entering the mixing channel. (iii) Two triangular barriers are placed within the mixing channel to impose chaotic advection and perturb the less-mixed flow along the top and bottom surfaces of the channel. (iv) Finally, two outlet channels are incorporated to discard the less-mixed flow. Three-dimensional simulations are carried out to evaluate the performance of the micromixer. Simulations are performed in the absence and presence of the gravitational force to analyse the influence of gravity on the micromixer. Mixing efficiencies of greater than 92 % are achieved using water and a low-density biological solvent as the mixing fluids.
Notes This paper was also presented at European Conference on Microfluidics (1st : 2008 : Bologna, Italy) on December 10-12, 2008.
Language eng
DOI 10.1051/lhb/2009088
Field of Research 091306 Microelectromechanical Systems (MEMS)
Socio Economic Objective 920203 Diagnostic Methods
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2009, Société Hydrotechnique de France
Persistent URL http://hdl.handle.net/10536/DRO/DU:30025583

Document type: Journal Article
Collection: School of Engineering
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Created: Thu, 25 Mar 2010, 10:02:04 EST by Abbas Kouzani

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