Bioactive hydroxyapatite coating on titanium-niobium alloy through a sol-gel process

Xiong, Jianyu, Li, Yuncang, Hodgson, Peter and Wen, Cui'e 2009, Bioactive hydroxyapatite coating on titanium-niobium alloy through a sol-gel process, Materials science forum, vol. 618-619, pp. 325-328, doi: 10.4028/

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Title Bioactive hydroxyapatite coating on titanium-niobium alloy through a sol-gel process
Author(s) Xiong, Jianyu
Li, Yuncang
Hodgson, Peter
Wen, Cui'e
Journal name Materials science forum
Volume number 618-619
Start page 325
End page 328
Total pages 4
Publisher Trans Tech
Place of publication Stafa-Zurich, Switzerland
Publication date 2009
ISSN 0255-5476
Keyword(s) titanium-niobium
Summary Hydroxyapatite (HA) was coated on the surface of a titanium-niobium (Ti-Nb) alloy by a sol-gel process. Triethyl phosphite and calcium nitrate were used as the phosphorus (P) and calcium (Ca) precursors respectively to prepare a Ca/P sol solution. The Ti-Nb alloy was dip-coated in the sol and heated at 600°C for 30 minutes. X-ray diffraction (XRD) analysis indicated the major phase constituent of the coating after heat treatment was HA. Scanning electron microscopy (SEM) observation showed that a few cracks were distributed on the HA coating. The in-vitro bioactivity of the HA coated Ti-Nb alloy was assessed using a cell culture of SaOS-2 osteoblast-like cells. The density of cell attachment was determined by MTT assay; the cell morphology was observed by SEM. Results indicated that the density of cell attachment on the surface of the Ti-Nb alloy was significantly increased by HA coating. Cell morphology observation showed that cells attached, spread and grew well on the HA coated surface. It can be concluded that the HA coating improved the in-vitro bioactivity of Ti-Nb alloy effectively.
Language eng
DOI 10.4028/
Field of Research 090301 Biomaterials
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
ERA Research output type C Journal article
HERDC collection year 2009
Copyright notice ©2009, Trans Tech Publications
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Document type: Journal Article
Collections: Centre for Material and Fibre Innovation
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