A potential application of a piezoelectric atomiser for ophthalmic drug delivery

Xia, Wei, Hsu, Hung-Yao, Kong, Lingxue, Evans, Allan and Lee, Ryan 2007, A potential application of a piezoelectric atomiser for ophthalmic drug delivery, Applied bionics and biomechanics, vol. 4, no. 1, pp. 9-17.


Title A potential application of a piezoelectric atomiser for ophthalmic drug delivery
Author(s) Xia, Wei
Hsu, Hung-Yao
Kong, Lingxue
Evans, Allan
Lee, Ryan
Journal name Applied bionics and biomechanics
Volume number 4
Issue number 1
Start page 9
End page 17
Total pages 10
Publisher Taylor & Francis
Place of publication Abingdon, England
Publication date 2007-03
ISSN 1176-2322
Summary A liquid atomiser composed of a piezoelectric transducer and a metal plate with numerous micro-apertures is studied to identify the most influential factors on its atomising performance. The Taguchi method is employed in the experiment design and analysis of the study on how each factor acts in the atomising process. An optimal condition is determined for producing a stream of droplets. The study shows that the droplet size and the spraying velocity are suitable for ophthalmic drug delivery application, with an even distribution of the drug over most of the eyeball surface area due to the controllable cross-sectional area of the droplet stream. This greatly improves the treatment effectiveness and efficiency of eye therapy. Finally, a structure of the ophthalmic drug delivery system is proposed.
Language eng
Field of Research 090304 Medical Devices
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2007, Taylor & Francis
Persistent URL http://hdl.handle.net/10536/DRO/DU:30026160

Document type: Journal Article
Collection: Centre for Material and Fibre Innovation
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