You are not logged in.

The miscibility of poly(d,l-lactide-co-glycolide) with amphiphilic molecules and the interaction of their mixtures with DNA at air/water interface

Sun, Lu, Xu, Miao and Wu, Lixin 2005, The miscibility of poly(d,l-lactide-co-glycolide) with amphiphilic molecules and the interaction of their mixtures with DNA at air/water interface, Colloids and surfaces B : biointerfaces, vol. 43, no. 1, pp. 29-35, doi: 10.1016/j.colsurfb.2005.03.013.

Attached Files
Name Description MIMEType Size Downloads

Title The miscibility of poly(d,l-lactide-co-glycolide) with amphiphilic molecules and the interaction of their mixtures with DNA at air/water interface
Author(s) Sun, LuORCID iD for Sun, Lu orcid.org/0000-0003-2999-1250
Xu, Miao
Wu, Lixin
Journal name Colloids and surfaces B : biointerfaces
Volume number 43
Issue number 1
Start page 29
End page 35
Total pages 7
Publisher Elsevier
Place of publication Amsterdam, Netherlands
Publication date 2005-06
ISSN 0927-7765
Summary The miscibility of poly(d,l-lactide-co-glycolide) (PLG) with three amphiphilic molecules and the interaction of the PLG/surfactant mixtures with DNA at air/water interface are investigated by π-A isotherms, Brewster angle microscopy (BAM) and atomic force microscopy (AFM) techniques. The π-A isotherms of the PLG mixtures with cationic C12AzoC6PyBr, and C12AzoC6N(CH3)3Br, are quite different from the π-A isotherm of pure PLG on water subphase. In contrast to the case, the π-A isotherm of PLG mixed with nonionic C12AzoC6OPy is almost identical to the pure PLG except some increasing of molecular area. Similar phenomena are observed on DNA subphase. The in situ BAM and ex situ AFM observations demonstrate that the dispersion of PLG at air/water interface becomes good when it mixes with the two cationic surfactants, whereas quite poor due to the phase separation when it mixes with the nonionic amphiphilic molecule. Based on these results we conclude that the cationic surfactants can affect the conformation change of PLG at air/water interface and figure a well miscibility with polymer whereas the nonionic amphiphilic molecule presents poor miscibility. In addition, the even mixing of the PLG and the cationic surfactants is favorable for the adsorption to DNA more effectively.
Language eng
DOI 10.1016/j.colsurfb.2005.03.013
Field of Research 060101 Analytical Biochemistry
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2005, Elsevier
Persistent URL http://hdl.handle.net/10536/DRO/DU:30026275

Document type: Journal Article
Collection: Centre for Material and Fibre Innovation
Connect to link resolver
 
Unless expressly stated otherwise, the copyright for items in DRO is owned by the author, with all rights reserved.

Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 1 times in TR Web of Science
Scopus Citation Count Cited 1 times in Scopus
Google Scholar Search Google Scholar
Access Statistics: 467 Abstract Views, 0 File Downloads  -  Detailed Statistics
Created: Tue, 30 Mar 2010, 10:46:53 EST

Every reasonable effort has been made to ensure that permission has been obtained for items included in DRO. If you believe that your rights have been infringed by this repository, please contact drosupport@deakin.edu.au.