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Mechanisms regulating the function of the ATP7B copper-ATPase

Cater, Michael Alan 2004, Mechanisms regulating the function of the ATP7B copper-ATPase, Ph.D. thesis, School of Biological and Chemical Sciences and Centre for Cellular and Molecular Biology, Deakin University.

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Title Mechanisms regulating the function of the ATP7B copper-ATPase
Author Cater, Michael Alan
Institution Deakin University
School School of Biological and Chemical Sciences
Centre for Cellular and Molecular Biology
Faculty Faculty of Science and Technology
Degree name Ph.D.
Date submitted 2004
Keyword(s) Copper - Physiological effect
Copper proteins
Copper enzymes
Metabolism, Inborn errors of
Liver - Diseases
Summary The copper-transporting ATP7B protein is defective in patients with Wilson disease, which causes the accumulation of toxic levels of copper in the body particularly in the liver. This thesis provides new information about how ATP7B maintains copper levels in the body within safe limits.
Language eng
Description of original xiii, 216 leaves : ill. ; 30 cm.
Dewey Decimal Classification 612.3924
Persistent URL http://hdl.handle.net/10536/DRO/DU:30026857

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