Analysis of the Stat5 genes in zebrafish

Lewis, Rowena Sue. 2006, Analysis of the Stat5 genes in zebrafish, Ph.D. thesis, School of Life and Environmental Sciences, Deakin University.

Title Analysis of the Stat5 genes in zebrafish
Author Lewis, Rowena Sue.
Institution Deakin University
School School of Life and Environmental Sciences
Faculty Faculty of Science and Technology
Degree name Ph.D.
Date submitted 2006
Keyword(s) Genetic regulation
Gene expression
Hematopoietic system
Summary This dissertation identified and characterised a key genetic regulator called Stat5 using zebrafish. Up-regulation of Stat5 led to an increase in blood cells, indicative of pre-leukaemia, whilst down-regulation decreased these cells and caused other defects. This work shows that Stat5 is critical in blood cell maturation and early embryonic development.
Notes Degree conferred 2007.
Language eng
Description of original ix, 211p. : ill. ; 30 cm.
Dewey Decimal Classification 572.865
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