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Arsenic induced regulation of base excision repair in human cells

Sykora, Peter. 2007, Arsenic induced regulation of base excision repair in human cells, Ph.D. thesis, School of Life and Environmental Sciences, Deakin University.


Title Arsenic induced regulation of base excision repair in human cells
Author Sykora, Peter.
Institution Deakin University
School School of Life and Environmental Sciences
Faculty Faculty of Science and Technology
Degree name Ph.D.
Date submitted 2007
Keyword(s) DNA repair
Cancer - Genetic aspects
Pathology, Molecular
Arsenic - Toxicology
Summary Short term exposure to low levels of arsenic in human cells increased the cells' capacity to repair its DNA. In turn, cells became resistant to the toxic effects of UV radiation. However prolonged increases in principal repair proteins may actually lead to cancerous effects by destabilizing DNA repair.
Notes Degree conferred 2008.
Language eng
Description of original 200 leaves ; 30 cm.
Dewey Decimal Classification 572.86459
Persistent URL http://hdl.handle.net/10536/DRO/DU:30027204

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Created: Thu, 01 Apr 2010, 15:55:05 EST

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