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AHI1 and NDRG2 function in skeletal muscle and the development of type 2 diabetes

Prior, Matthew J. 2008, AHI1 and NDRG2 function in skeletal muscle and the development of type 2 diabetes, Ph.D. thesis, School of Exercise and Nutrition Sciences, Deakin University.


Title AHI1 and NDRG2 function in skeletal muscle and the development of type 2 diabetes
Author Prior, Matthew J.
Institution Deakin University
School School of Exercise and Nutrition Sciences
Faculty Faculty of Health, Medicine, Nursing and Behavioural Sciences
Degree name Ph.D.
Date submitted 2008
Keyword(s) Genetic regulation
Non-insulin-dependent diabetes - Genetic aspects
Glucose - Physiological transport
Striated muscle - Metabolism
Cell metabolism
Summary In this study, AHI1 and NDRG2 gene function in the insulin signalling pathways regulating skeletal muscle homeostasis was investigated. Findings implicate AHI1 in the regulation of insulin-stimulated glucose transport and the development of insulin resistance, whilst associating NDRG2 with the regulation of myoblast proliferation and differentiation; possible via interactions with PICK1 and arfaptin2.
Notes Degree conferred 2009.
Language eng
Description of original xiv, 229 leaves ; 30 cm.
Dewey Decimal Classification 572.86519
Persistent URL http://hdl.handle.net/10536/DRO/DU:30027346

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Created: Thu, 01 Apr 2010, 15:57:40 EST

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