Dissecting the role of SOCS proteins using zebrafish

O'Sullivan, Lynda Anne. 2008, Dissecting the role of SOCS proteins using zebrafish, Ph.D. thesis, School of Life and Environmental Sciences, Deakin University.

Title Dissecting the role of SOCS proteins using zebrafish
Author O'Sullivan, Lynda Anne.
Institution Deakin University
School School of Life and Environmental Sciences
Faculty Faculty of Science and Technology
Degree name Ph.D.
Date submitted 2008
Keyword(s) Cytokinesis
Zebra danios as laboratory animals
Animal models in research
Cancer - Animal models
Inflammation - Animal models
Summary Suppressors of cytokine signalling (SOCS) proteins are negative regulators of the JAK-STAT pathway which is perturbed in certain disease states including cancers and inflammatory diseases. This thesis ascertained the suitability of zebrafish as an alternative animal model to study the SOCS proteins which established new and additional roles during development.
Notes Degree conferred 2009.
Language eng
Description of original xv, 180 leaves : ill. ; 30 cm.
Dewey Decimal Classification 571.844
Persistent URL http://hdl.handle.net/10536/DRO/DU:30027358

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