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Evolution of class I cytokine receptor signalling : conservation of GCSFR

Liongue, Clifford. 2008, Evolution of class I cytokine receptor signalling : conservation of GCSFR, Ph.D. thesis, School of Medicine, Deakin University.


Title Evolution of class I cytokine receptor signalling : conservation of GCSFR
Author Liongue, Clifford.
Institution Deakin University
School School of Medicine
Faculty Faculty of Health, Medicine, Nursing and Behavioural Sciences
Degree name Ph.D.
Date submitted 2008
Keyword(s) Cytokines - Physiological effect
Granulocytes
Cellular signal transduction
Summary Cytokines are proteins that provide essential signals to blood and immune cells. The evolution of this system was determined from primitive organisms to humans and zebrafish. Analysis of zebrafish granulocyte colony-stimulating factor (GCSF) signalling revealed broad conservation of function with mammals and a novel role in white blood cell migration.
Notes Degree conferred 2009.
Language eng
Description of original xii, 249 leaves ; 30 cm.
Dewey Decimal Classification 571.968
Persistent URL http://hdl.handle.net/10536/DRO/DU:30027397

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Created: Thu, 01 Apr 2010, 15:58:37 EST

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