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Differential gene expression in the skeletal muscle of Psammomys obesis

Mack, Suzanne. 2000, Differential gene expression in the skeletal muscle of Psammomys obesis, M.Sc. thesis, School of Health Sciences, Deakin University.

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Title Differential gene expression in the skeletal muscle of Psammomys obesis
Author Mack, Suzanne.
Institution Deakin University
School School of Health Sciences
Faculty Faculty of Health and Behavioural Sciences
Degree name M.Sc.
Date submitted 2000
Keyword(s) Diabetes - Genetic aspects
Gene expression
Summary Focuses on discovering and investigating altered gene expression in the skeletal muscle of Psammomys obesus which is a unique model of obesity and Type II diabetes in which its development is similar to that of the human population. Defects in the skeletal muscle are pivotal to the development of Type II diabetes. Using the latest techniques in molecular biology the regulation of a number of genes was confirmed to be altered in obese or diabetic animals compared to lean. This indicates that changes to gene expression contribute to the metabolic disturbances associated with obesity and Type II diabetes.
Language eng
Description of original xii, 131 leaves : ill. ; 30 cm.
Dewey Decimal Classification 572.8651
Persistent URL http://hdl.handle.net/10536/DRO/DU:30027926

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Created: Thu, 01 Apr 2010, 16:07:50 EST

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