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The case | Allograft dysfunction in a patient with sickle cell disease

O'Rourke, E.J., Laing, C.M., Khan, A.U., Hussain, R., Standish, R.A., Buscombe, J.R., Hilson, A.J. and Harber, M. 2008, The case | Allograft dysfunction in a patient with sickle cell disease, Kidney international, vol. 74, no. 9, pp. 1219-20, doi: 10.1038/ki.2008.387.

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Title The case | Allograft dysfunction in a patient with sickle cell disease
Author(s) O'Rourke, E.J.
Laing, C.M.
Khan, A.U.
Hussain, R.
Standish, R.A.
Buscombe, J.R.
Hilson, A.J.
Harber, M.
Journal name Kidney international
Volume number 74
Issue number 9
Start page 1219
End page 20
Publisher Nature Publishing Group
Place of publication London, England
Publication date 2008-11
ISSN 0085-2538
1523-1755
Summary The article focuses on the study concerning the diagnosis of acute renal allograft in patient with sickle cell disease. The 33 year old underwent several surgeries with immediate graft function. The percutaneous renal biopsy of the patient shows focal cortical necrosis and acute tubular damage coherent with ischemia. It concludes that the allograft sickling is the primary cause of the acute renal dysfunction in patients with sickle cell disease.
Language eng
DOI 10.1038/ki.2008.387
Field of Research 110312 Nephrology and Urology
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©2008, Nature Publishing Group
Persistent URL http://hdl.handle.net/10536/DRO/DU:30028203

Document type: Journal Article
Collections: Faculty of Health
School of Medicine
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