Mixing characterisation for a serpentine microchannel equipped with embedded barriers
Khoshmanesh, K., Tovar-Lopez, F. J., Nasabi, M., Kouzani, A., Nahavandi, S., Kanwar, J., Baratchi, S., Kalantar-zadeh, K. and Mitchell, A. 2008, Mixing characterisation for a serpentine microchannel equipped with embedded barriers, in SPIE 2008 : Progress in biomedical optics and imaging : Proceedings of SPIE Biomedical Applications of Micro- and Nanoengineering IV and Complex Systems conference, SPIE : The International Society for Optical Engineering, Bellingham, Wash., pp. 727005-1-727005-11.
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This paper describes the design, simulation, fabrication and experimental analysis of a passive micromixer for the mixing of biological solvents. The mixer consists of a T-junction, followed by a serpentine microchannel. the serpentine has three arcs, each equipped with circular barriers that are patterned as two opposing triangles. >The barriers are engineered to induce periodic perturbations in the flow field and enhance the mixing. CFD (Computational Fluid Dynamics) method is applied to optimise the geometric variables of the mixer before fabrication. The mixer is made from PDMS (Polydimethylsiloxane) using photo- and soft-lithography techniques. Experimental measurements are performed using yellow and blue food dyes as the mixing fluids. The mixing is measured by analysing the composition of the flow's colour across the outlet channel. The performance of the mixer is examined in a wide range of flow rates from 0.5 to 10 µl/min. Mixing efficiencies of higher than 99.4% are obtained in the experiments confirming the results of numerical simulations. The proposed mixer can be employed as a part of lab-on-a-chip for biomedical applications.
Field of Research
091306 Microelectromechanical Systems (MEMS)
Socio Economic Objective
861503 Scientific Instruments
HERDC Research category
E2.1 Full written paper - non-refereed / Abstract reviewed
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