Aptasensors : a review

Lim, Y. C., Kouzani, A. Z. and Duan, W. 2010, Aptasensors : a review, Journal of biomedical nanotechnology, vol. 6, no. 2, pp. 93-105.

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Title Aptasensors : a review
Author(s) Lim, Y. C.
Kouzani, A. Z.
Duan, W.
Journal name Journal of biomedical nanotechnology
Volume number 6
Issue number 2
Start page 93
End page 105
Total pages 13
Publisher American Scientific Publishers
Place of publication Valencia, Calif.
Publication date 2010-04
ISSN 1550-7033
1550-7041
Keyword(s) aptasensor
aptamer
immobilization
reporter
optical
electrochemical
electrical
mass-sensitive
micromechanical
Summary Aptamers are a promising class of agents for biomolecules detection due to their small size, chemical stability and cost effectiveness over conventional bioreceptors such as antibodies. Recent advances in micro/nano-fabrication and biotechnology have driven active participation of engineers and molecular biologists in the development of aptasensors. This review examines aptasensors from a developer standpoint discussing surface immobilization techniques and mechanisms used to detect biomolecular interactions in the context of biotechnology and nanomedicine. The factors that affect accuracy, sensitivity and stability of aptasensors are also addressed.
Language eng
Field of Research 100402 Medical Biotechnology Diagnostics (incl Biosensors)
090604 Microelectronics and Integrated Circuits
091306 Microelectromechanical Systems (MEMS)
Socio Economic Objective 861502 Medical Instruments
HERDC Research category C1 Refereed article in a scholarly journal
HERDC collection year 2010
Copyright notice ©2010, American Scientific Publishers
Persistent URL http://hdl.handle.net/10536/DRO/DU:30029436

Document type: Journal Article
Collections: School of Medicine
School of Engineering
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Created: Thu, 22 Jul 2010, 17:03:42 EST by Abbas Kouzani

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