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Effects of design parameters on sensitivity of microcantilever biosensors

Lim, Yang-Choon, Kouzani, Abbas Z., Duan, Wei and Kaynak, Akif 2010, Effects of design parameters on sensitivity of microcantilever biosensors, in IEEE/ICME 2010 : Proceedings of the 2010 International Conference on Complex Medical Engineering, IEEE, [Gold Coast, Queensland], pp. 177-181.

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Title Effects of design parameters on sensitivity of microcantilever biosensors
Author(s) Lim, Yang-Choon
Kouzani, Abbas Z.
Duan, Wei
Kaynak, Akif
Conference name IEEE/ICME International Conference on Complex Medical Engineering (2010 : Gold Coast, Australia)
Conference location Gold Coast, Australia
Conference dates 13-15 July, 2010
Title of proceedings IEEE/ICME 2010 : Proceedings of the 2010 International Conference on Complex Medical Engineering
Editor(s) Li, Yan
Yang, Jiajia
Wen, Peng
Wu, Jinglong
Publication date 2010
Conference series IEEE/ICME International Conference on Complex Medical Engineering
Start page 177
End page 181
Total pages 5
Publisher IEEE
Place of publication [Gold Coast, Queensland]
Keyword(s) Biosensor
Microcantilever
Sensitivity
Summary Microcantilever biosensors produce cantilever bending due to differential surface stress between upper and lower surfaces of the cantilever. The bending is associated with concentration of ligands and adsorbed ligand-receptor intermolecular forces. Sample volume sizes in clinical diagnostic applications are usually very minute requiring a highly sensitive microcantilever for disease detection. This paper investigates a number of parameters that influence the sensitivity of microcantilever biosensors. The parameters include length, thickness, shape, and material of the cantilever beam. Biosensors of varying parameters are modeled and simulated. The results show that increasing the length of the cantilever beam enhances its sensitivity. However, increasing the thickness of the cantilever beam reduces its sensitivity. In static analysis, the shape of the cantilever beam does not notably impact upon its sensitivity. Also, using materials with lower Young’s modulus improves the sensitivity.
Notes This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.
ISBN 9781424468423
Language eng
Field of Research 091306 Microelectromechanical Systems (MEMS)
090304 Medical Devices
090601 Circuits and Systems
Socio Economic Objective 920203 Diagnostic Methods
HERDC Research category E1 Full written paper - refereed
HERDC collection year 2010
Copyright notice ©2010, IEEE.
Persistent URL http://hdl.handle.net/10536/DRO/DU:30029821

Document type: Conference Paper
Collections: School of Medicine
School of Engineering
Open Access Collection
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Created: Tue, 24 Aug 2010, 21:39:09 EST by Abbas Kouzani

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