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Parameter sensitivity analysis of surface plasmon resonance biosensor through numerical simulation

Islam, Md. Saiful, Kouzani, Abbas Z., Dai, Xiu J. and Michalski, Wojtek P. 2010, Parameter sensitivity analysis of surface plasmon resonance biosensor through numerical simulation, in IEEE/ICME 2010 : Proceedings of the 2010 IEEE/ICME International Conference on Complex Medical Engineering, IEEE, Gold Coast, Queensland, pp. 171-176.

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Title Parameter sensitivity analysis of surface plasmon resonance biosensor through numerical simulation
Author(s) Islam, Md. Saiful
Kouzani, Abbas Z.
Dai, Xiu J.
Michalski, Wojtek P.
Conference name IEEE/ICME International Conference on Complex Medical Engineering (2010 : Gold Coast, Queensland)
Conference location Gold Coast, Queensland
Conference dates 13-15 Jul. 2010
Title of proceedings IEEE/ICME 2010 : Proceedings of the 2010 IEEE/ICME International Conference on Complex Medical Engineering
Editor(s) Li, Yan
Yang, Jiajia
Wen, Peng
Wu, Jinglong
Publication date 2010
Conference series IEEE/ICME International Conference on Complex Medical Engineering
Start page 171
End page 176
Total pages 324 p.
Publisher IEEE
Place of publication Gold Coast, Queensland
Keyword(s) Biosensor
Surface Plasmon Resonance
Numerical Simulation
Summary Surface based analytical tools have gained more importance for rapid, sensitive and label-free monitoring of molecular recognition events. Surface plasmon resonance (SPR) has played a prominent role in real time monitoring of surface binding events. SPR is increasing its significance especially for the study of ultrathin dielectric layer. This paper investigates the role of thin films of gold, silver and aluminium for protein detection in SPR biosensors. It is shown that the sensitivity, which is indicated by the shift of plasmon dip, is not linearly related to the thickness of protein but quadratic over a specific range. The approach involves a plot of a reflectivity curve as a function of the angle of incidence.
Notes Conference website - http://www.usq.edu.au/cme2010
ISBN 9781424468423
Language eng
Field of Research 091306 Microelectromechanical Systems (MEMS)
090601 Circuits and Systems
090304 Medical Devices
Socio Economic Objective 860902 Veterinary Diagnostics
HERDC Research category E1 Full written paper - refereed
HERDC collection year 2010
Copyright notice ©2010, IEEE
Persistent URL http://hdl.handle.net/10536/DRO/DU:30029823

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Created: Tue, 24 Aug 2010, 22:33:14 EST by Abbas Kouzani

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