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Biodegradable Mg-Ca and Mg-Ca-Y alloys for regenerative medicine

Li, Yuncang, Li, Meiheng, Hu, Wangyu, Hodgson, Peter and Wen, Cui'e 2010, Biodegradable Mg-Ca and Mg-Ca-Y alloys for regenerative medicine, Materials science forum, vol. 654-656, pp. 2192-2195, doi: 10.4028/www.scientific.net/MSF.654-656.2192.

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Title Biodegradable Mg-Ca and Mg-Ca-Y alloys for regenerative medicine
Author(s) Li, Yuncang
Li, Meiheng
Hu, Wangyu
Hodgson, Peter
Wen, Cui'e
Journal name Materials science forum
Volume number 654-656
Start page 2192
End page 2195
Total pages 4
Publisher Trans Tech Publications Ltd.
Place of publication Stafa-Zurich, Switzerland
Publication date 2010-06-30
ISSN 0255-5476
1422-6375
Keyword(s) biodegradable
magnesium alloys
mechanical property
cytotoxicity
Summary In this study, Mg-xCa (x = 0.5, 1.0, 2.0, 5.0, 10.0, 15.0 and 20.0 %, wt.%, hereafter) and Mg-1Ca-1Y alloys were investigated as new biodegradable bone implant materials. The compressive strength, ultimate strength and hardness of the Mg-Ca alloys increased, whilst the corrosion rate and biocompatibility decreased, with the increase of the Ca content in the Mg-Ca alloys; higher Ca content caused the Mg-Ca alloy to become brittle. Solutions of simulated body fluid (SBF) and modified minimum essential media (MMEM) with the immersion of Mg-xCa and Mg-1Ca-1Y alloys showed strong alkalisation. The yttrium addition to the Mg-Ca alloys does not improve the corrosion resistance of the Mg-1Ca-1Y alloy as expected compared to the Mg-1Ca alloy. It is suggested that Mg-Ca alloys with Ca additions less than 1.0 wt.% exhibited good biocompatibility and low corrosion rate.
Language eng
DOI 10.4028/www.scientific.net/MSF.654-656.2192
Field of Research 090301 Biomaterials
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1 Refereed article in a scholarly journal
HERDC collection year 2010
Copyright notice ©2010, Trans Tech Publications, Switzerland
Persistent URL http://hdl.handle.net/10536/DRO/DU:30030446

Document type: Journal Article
Collection: Centre for Material and Fibre Innovation
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Created: Mon, 11 Oct 2010, 15:57:20 EST by Sandra Dunoon

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