Investigation of JAK/STAT signaling in human skeletal muscle

Trenerry, Marissa K. 2009, Investigation of JAK/STAT signaling in human skeletal muscle, Ph.D. thesis, School of Exercise and Nutrition Sciences, Deakin University.

Title Investigation of JAK/STAT signaling in human skeletal muscle
Author Trenerry, Marissa K.
Institution Deakin University
School School of Exercise and Nutrition Sciences
Faculty Faculty of Health, Medicine, Nursing and Behavioural Sciences
Degree name Ph.D.
Date submitted 2009
Keyword(s) Striated muscle - Metabolism
Exercise - Physiological aspects
Summary Understanding muscle adaptation and repair is vital for preserving muscle loss with aging. Analysis of the inflammatory-responsive signalling pathway, JAK/STAT was performed. After intense exercise, the STAT3 pathway is highly activated, potentially by the pro-inflammatory regulator IL-6. This pathway is suppressed in older individuals, possible leading to altered inflammatory regulation.
Notes Degree conferred 2010.
Language eng
Description of original xviii, 131 p ; 30 cm.
Dewey Decimal Classification 611.0186
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