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Ikaros gene family : characterisation of the 'atypical' Pegasus

John, Liza Bernadine 2010, Ikaros gene family : characterisation of the 'atypical' Pegasus, Ph.D. thesis, School of Medicine, Deakin University.


Title Ikaros gene family : characterisation of the 'atypical' Pegasus
Author John, Liza Bernadine
Institution Deakin University
School School of Medicine
Faculty Faculty of Health, Medicine, Nursing and Behavioural Sciences
Degree name Ph.D.
Date submitted 2010
Keyword(s) Transcription factors
Immune response - Regulation - Genetic aspects
Hematopoiesis - Genetic aspects
Summary Ikaros-related transcription factors are essential for adaptive immunity. Evolutionary analysis suggested derivation from a precursor similar to the 'atypical' Pegasus protein, and possibly related to invertebrate Hunchback. Pegasus was shown to regulate neural, gut and blood cell development in zebrafish, with Ikaros identified as one of several potential gene targets.
Language eng
Description of original xix, 221 leaves : ill. ; 30 cm.
Dewey Decimal Classification 572.8845
Persistent URL http://hdl.handle.net/10536/DRO/DU:30030611

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Created: Fri, 15 Oct 2010, 14:12:30 EST

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