Effect of a stearic acid-rich, structured triacylglycerol on plasma lipid concentrations

Nestel, Paul J., Pomeroy, Sylvia, Kay, Sally, Sasahara, Takayuki and Yamashita, Takeshi 1998, Effect of a stearic acid-rich, structured triacylglycerol on plasma lipid concentrations, The American journal of clinical nutrition, vol. 68, no. 6, pp. 1196-1201.

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Title Effect of a stearic acid-rich, structured triacylglycerol on plasma lipid concentrations
Author(s) Nestel, Paul J.
Pomeroy, Sylvia
Kay, Sally
Sasahara, Takayuki
Yamashita, Takeshi
Journal name The American journal of clinical nutrition
Volume number 68
Issue number 6
Start page 1196
End page 1201
Publisher American Society for Nutrition
Place of publication Bethesda, Md.
Publication date 1998-12
ISSN 0002-9165
1938-3207
Summary Background: Structured lipids are being incorporated into foods to reduce their energy value. One such lipid is rich in stearic acid.
Objective: The objective of this study was to compare the effects on plasma lipids of a stearic acid–rich triacylglycerol and a fat rich in palmitic acid in hypercholesterolemic subjects.
Design: Fifteen subjects with an average plasma cholesterol concentration of 6.13 ± 0.80 mmol/L initially ate a low-fat diet for 2 wk (run-in period), followed in random order and blinded fashion by 2 high-fat diets (for 5 wk each) containing foods derived from margarines rich either in palmitic acid or in the structured, stearic acid–rich triacylglycerol.
Results: Plasma cholesterol concentrations with the low-fat, the stearic acid–rich, and the palmitic acid–rich diets were not significantly different (5.35 ± 0.83, 5.41 ± 0.78, and 5.52 ± 0.68 mmol/L, respectively) but were significantly lower (P < 0.001) than those measured during the habitual diet period (ie, 2 wk before the study began). Neither HDL cholesterol nor plasma triacylglycerol differed significantly among the 3 study diets.
Conclusion: A similar increase in the intake of stearic and palmitic acids (differing by <5% of total energy) to ensure a high fat intake resulted in plasma total and LDL-cholesterol concentrations that did not differ significantly from concentrations measured during a period of low-fat intake.
Language eng
Field of Research 110199 Medical Biochemistry and Metabolomics not elsewhere classified
Socio Economic Objective 970111 Expanding Knowledge in the Medical and Health Sciences
HERDC Research category C1.1 Refereed article in a scholarly journal
Copyright notice ©1998, American Society for Clinical Nutrition
Persistent URL http://hdl.handle.net/10536/DRO/DU:30030889

Document type: Journal Article
Collection: School of Exercise and Nutrition Sciences
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