Predicting time trade-off health state valuations of adolescents in four Pacific countries using the assessment of quality-of-life (AQoL-6D) instrument

Moodie, Marj, Richardson, Jeff, Rankin, Bree, Lezzi, Angelo and Kompal, Sinha 2010, Predicting time trade-off health state valuations of adolescents in four Pacific countries using the assessment of quality-of-life (AQoL-6D) instrument, Value in health, vol. 13, no. 8, pp. 1014-1027.

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Title Predicting time trade-off health state valuations of adolescents in four Pacific countries using the assessment of quality-of-life (AQoL-6D) instrument
Author(s) Moodie, Marj
Richardson, Jeff
Rankin, Bree
Lezzi, Angelo
Kompal, Sinha
Journal name Value in health
Volume number 13
Issue number 8
Start page 1014
End page 1027
Total pages 14
Publisher Wiley-Blackwell
Place of publication Malden, Mass.
Publication date 2010-12-13
ISSN 1098-3015
1524-4733
Keyword(s) adolescents
ethnicity
Pacific
quality of life
utility weights
Summary Objectives: Pacific Obesity Prevention in Communities (OPIC) is a community-based intervention project targeting adolescent obesity in Australia, New Zealand, Fiji, and Tonga. The Assessment of Quality of Life Mark 2 (AQoL-6D) instrument was completed by 15,481 adolescents to obtain a description of the quality of life associated with adolescent overweight and obesity, and a corresponding utility score for use in a cost–utility analysis of the interventions. This article describes the recalibration of this utility instrument for adolescents in each country.

Methods: The recalibration was based on country-specific time trade-off (TTO) data for 30 multiattribute health states constructed from the AQoL-6D descriptive system. Senior secondary students, in a classroom setting, responded to 10 health state scenarios each. These TTO interviews were conducted for 24 groups, comprising 279 students in the four countries resulting in 2790 completed TTO scores. The TTO scores were econometrically transformed by regressing the TTO scores upon predicted scores from the AQoL-6D to produce country-specific algorithms. The latter incorporated country-specific “corrections” to the Australian adult utility weights in the original AQoL.

Results: This article reports two methodological elements not previously reported. The first is the econometric modification of an extant multi-attribute utility instrument to accommodate cultural and other group-specific differences in preferences. The second is the use of the TTO technique with adolescents in a classroom group setting. Significant differences in utility scores were found between the four countries.

Conclusion: Statistical results indicate that the AQoL-6D can be validly used in the economic evaluation of both the OPIC interventions and other adolescent programs.
Notes Article first published online 3 Sep 2010
Language eng
Field of Research 140208 Health Economics
Socio Economic Objective 920207 Health Policy Economic Outcomes
HERDC Research category C1 Refereed article in a scholarly journal
Copyright notice ©2010, International Society for Pharmacoeconomics and Outcomes Research
Persistent URL http://hdl.handle.net/10536/DRO/DU:30031019

Document type: Journal Article
Collection: Public Health Research, Evaluation, and Policy Cluster
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